Camptosar , Irinotecan Hydrochloride

SECTION 2: Hazards identification

NFPA Rating Classification GHS Acute toxicity, Oral (Category 4) Eye Irritation (Category 2B) Toxic to Reproduction (Category 1B) Mutagenicity (Category 2) Target Organ Toxicity (Category 2) NFPA Rating

Health hazards

Fire Hazard Reactivity Hazard Signal Word, Hazard Description of Hazards statement(s), Symbol(s), and/or Precautionary statement(s)

Signal word

WARNING Hazard Statements N/A May cause eye, skin, or respiratory system irritation Suspected of damaging fertility or the unborn child Suspected of causing genetic defects if ingested May cause damage to the bone marrow, gastrointestinal system, central nervous system, cardiovascular system, lungs, liver, and skin through prolonged or repeated exposure

Prevention

- Obtain special instructions before use. - Do not handle until all safety precautions have been read and understood. - Use personal protective equipment as required. - Do not eat, drink or smoke when using this product. - Wash hands thoroughly after handling. - Do not breathe vapors or spray.

Response

- IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. If eye irritation persists, get medical attention. - IF exposed or concerned, get medical attention. (d) Unknown Acute Toxicity: N/A

2.1 Classification of the substance or mixture

GHS: Acute toxicity, Oral (Category 4) Eye Irritation (Category 2B) Toxic to Reproduction (Category 1B) Mutagenicity (Category 2) Target Organ Toxicity (Category 2) NFPA Rating Health Hazard 2 Fire Hazard 0 Reactivity Hazard 0 (b) Signal Word, Hazard (c) Description of Hazards