KALEX 14536 PART A

Hazardous Ingredients

CAS Number METHYLENE BIS (PHENYLISOCYANATE)(MDI) 101-68-8 *** ALL Ingredients in this product are listed in the T.S.C.A. Inventory SECTION III - HAZARDS IDENTIFICATION EYE CONTACT: MAY CAUSE MODERATE EYE IRRITATION. MAY CAUSE VERY SLIGHT TRANSIENT (TEMPORARY) CORNEAL INJURY. SKIN CONTACT: PROLONGED OR REPEATED SKIN CONTACT MAY CAUSE SKIN IRRITATION. MAY CAUSE ALLERGIC SKIN REACTION IN SUSCEPTIBLE INDIVIDUALS. ANIMAL STUDIES HAVE SHOWN THAT SKIN CONTACT WITH ISOCYANATES MAY PLAY A ROLE IN RESPIRATORY SENSITIZATION. MAY STAIN SKIN. A SINGLE PROLONGED EXPOSURE IS NOT LIKELY TO RESULT IN THE MATERIAL BEING ABSORBED IN HARMFUL AMOUNTS. INHALATION: AT ROOM TEMPERATURE, VAPORS ARE MINIMAL DUE TO LOW VAPOR PRESSURE. HOWEVER, CERTAIN OPERATIONS MAY GENERATE VAPOR OR AEROSOL CONCENTRATIONS SUFFICIENT TO CAUSE IRRITATION OR OTHER ADVERSE EFFECTS. SUCH OPERATIONS INCLUDE THOSE IN WHICH THE MATERIAL IS HEATED, SPRAYED OR OTHERWISE MECHANICALLY DISPERSED SUCH AS DRUMMING, VENTING OR PUMPING. EXCESSIVE EXPOSURE MAY CAUSE IRRITATION TO THE UPPER RESPIRATORY TRACT AND LUNGS, AND PULMONARY EDEMA. MAY CAUSE RESPIRATORY SENSITIZATION IN SUSCEPTIBLE INDIVIDUALS. MDI CONCENTRATIONS BELOW THE EXPOSURE GUIDELINES MAY CAUSE ALLERGIC RESPIRATORY REACTIONS IN INDIVIDUALS ALREADY SENSITIZED. SYMPTOMS MAY INCLUDE COUGHING, DIFFICULT BREATHING AND A FEELING OF TIGHTNESS IN THE CHEST. EFFECTS MAY BE DELAYED. DECREASED LUNG FUNCTION HAS BEEN ASSOCIATED WITH OVEREXPOSURE TO ISOCYANATES. INGESTION: SINGLE DOSE ORAL TOXICITY IS CONSIDERED TO BE LOW. HEALTH HAZARD INFORMATION: OTHER HEALTH INFORMATION (POLYMERIC MDI): TISSUE INJURY IN THE UPPER RESPIRATORY TRACT AND LUNGS HAS BEEN OBSERVED IN LABORATORY ANIMALS AFTER REPEATED EXCESSIVE EXPOSURES TO MDI/POLYMERIC MDI AEROSOLS. LUNG TUMORS HAVE BEEN OBSERVED IN LABORATORY ANIMALS EXPOSED TO AEROSOL DROPLETS OF MDI/POLYMERIC MDI FOR THEIR LIFETIME. TUMORS OCCURRED CONCURRENTLY WITH RESPIRATORY IRRITATION AND LUNG INJURY. CURRENT EXPOSURE GUIDELINES ARE EXPECTED TO PROTECT AGAINST THESE EFFECTS REPORTED FOR MDI. IN LABORATORY ANIMALS, MDI/POLYMERIC MDI DID NOT PRODUCE BIRTH DEFECTS; OTHER FETAL EFFECTS OCCURRED ONLY AT HIGH DOSES WHICH WERE TOXIC TO THE MOTHER.