ROTI Zol RNA ready-to-use, for molecular bio- logy

Hazard statements (CLP)

H290, H302, H302+H312+H332, H312, H314, H318, H332, H341, H373, H411

Code

Statements

H290

May be corrosive to metals

SECTION 2: Hazards identification

According to Regulation (EC) No 1272/2008 [CLP Classification of the substance or mixture

Hazard categories

Cat- Hazard class and Hazard egory category statement 2.16 Substance or mixture corrosive to metals Met. Corr. 1 H290 3.1O Acute toxicity (oral) Acute Tox. 4 H302 3.1D Acute toxicity (dermal) Acute Tox. 4 H312 3.1I Acute toxicity (inhal.) Acute Tox. 4 H332 3.2 Skin corrosion/irritation 1B Skin Corr. 1B H314 3.3 Serious eye damage/eye irritation Eye Dam. 1 H318 3.5 Germ cell mutagenicity Muta. 2 H341 3.9 Specific target organ toxicity - repeated exposure STOT RE 2 H373 4.1C Hazardous to the aquatic environment - chronic hazard Aquatic Chronic 2 H411 Supplemental hazard information Code Supplemental hazard information EUH032 contact with acids liberates very toxic gas EUH208 contains 8-Hydroxyquinoline. May produce an allergic reaction For full text of abbreviations: see SECTION 16

Most important adverse effects

Skin corrosion produces an irreversible damage to the skin; namely, visible necrosis through the epi- dermis and into the dermis. Delayed or immediate effects can be expected after short or long-term exposure. Spillage and fire water can cause pollution of watercourses

Signal word

Danger Danger Not required

Hazard pictograms

GHS05, GHS07, GHS08, GHS09 H314 Causes severe skin burns and eye damage. H341 Suspected of causing genetic defects. P280 Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308+P313 IF exposed or concerned: Get medical advice/attention. EUH032 Contact with acids liberates very toxic gas. EUH208

Hazard statements

H290 May be corrosive to metals H302+H312+H332 Harmful if swallowed, in contact with skin or if inhaled H314 Causes severe skin burns and eye damage H341 Suspected of causing genetic defects H373 May cause damage to organs through prolonged or repeated exposure H411 Toxic to aquatic life with long lasting effects Not required

Prevention

P270 Do not eat, drink or smoke when using this product P280 Wear protective gloves/protective clothing/eye protection/face protection

Response

P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower] P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P308+P313 IF exposed or concerned: Get medical advice/attention For professional users only

Supplemental label elements

EUH032 Contact with acids liberates very toxic gas. EUH208

Contains

8-Hydroxyquinoline. May produce an allergic reaction 8-Hydroxyquinoline. May produce an allergic reaction Phenol, Ammonium thiocyanate, Acetic acid ...%, 8-Hydroxyquinoline Labelling of packages where the contents do not exceed 10 ml

Hazardous Ingredients

Phenol, Ammonium thiocyanate, Acetic acid ...%, 8-Hydroxyquinoline Labelling of packages where the contents do not exceed 125 ml

Precautionary statements

Not required

Results of PBT and vPvB assessment

Does not contain a PBT-/vPvB-substance at a concentration of ≥ 0,1%. Endocrine disrupting properties Does not contain an endocrine disruptor (ED) at a concentration of ≥ 0,1%.

2.1 Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008 (CLP) Section Hazard class Cat- Hazard class and Hazard egory category statement 2.16 Substance or mixture corrosive to metals 1 Met. Corr. 1 H290 3.1O Acute toxicity (oral) 4 Acute Tox. 4 H302 3.1D Acute toxicity (dermal) 4 Acute Tox. 4 H312 3.1I Acute toxicity (inhal.) 4 Acute Tox. 4 H332 3.2 Skin corrosion/irritation 1B Skin Corr. 1B H314 3.3 Serious eye damage/eye irritation 1 Eye Dam. 1 H318 3.5 Germ cell mutagenicity 2 Muta. 2 H341 3.9 Specific target organ toxicity - repeated exposure 2 STOT RE 2 H373 4.1C Hazardous to the aquatic environment - chronic hazard 2 Aquatic Chronic 2 H411 Supplemental hazard information Code Supplemental hazard information EUH032 contact with acids liberates very toxic gas EUH208 contains 8-Hydroxyquinoline. May produce an allergic reaction For full text of abbreviations: see SECTION 16 The most important adverse physicochemical, human health and environmental effects Skin corrosion produces an irreversible damage to the skin; namely, visible necrosis through the epi- dermis and into the dermis. Delayed or immediate effects can be expected after short or long-term exposure. Spillage and fire water can cause pollution of watercourses.