Note: Ingredients listed on restricted chemical lists
EC/CAS
215-607-8/1333-82-0
Name of the chemical
Chromium trioxide
Concentration
>=3-<5 >=1%
General Information
Revision date
2026-05-27
Product name
Oxidizer
1.2.2. Uses advised against
For use as part of an IVD method, only on use
Emergency telephone
+44 (0)808 100 1920, +44 344 892 0111, +44 845 4647111
Icons in SDS
Company Information
company name
Roche Diagnostics Limited
e-mail address of the competent person responsible for the Safety Data Sheet
burgesshill.customerservice@roche.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H290, H302, H302+H312+H332, H312, H314, H317, H318, H332, H334, H335, H340, H350, H361f, H373, H411
Hazard statements
Code
Statements
H290
May be corrosive to metals
Section 2
SECTION 2: Hazards identification
Regulation (EC) No. 1272/2008 Classification of the substance or mixture
Signal word
Danger
Hazard statements
H290 May be corrosive to metals. H302 + H312 + H332 Harmful if swallowed, in contact with skin or if inhaled. H314 Causes severe skin burns and eye damage. H317 May cause an allergic skin reaction. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H335 May cause respiratory irritation. H340 May cause genetic defects. H350 May cause cancer. H361f Suspected of damaging fertility. H373 May cause damage to organs through prolonged or repeated exposure. H411 Toxic to aquatic life with long lasting effects.
Prevention
P201 Obtain special instructions before use. P260 Do not breathe mist or vapours. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
Response
P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P342 + P311 If experiencing respiratory symptoms: Call a POISON CENTER/ doctor. P391 Collect spillage.
Hazardous Ingredients
Chromium trioxide
Additional information
Restricted to professional users.
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
2.1 Classification of the substance or mixture
Classification (REGULATION (EC) No 1272/2008) as amended by GB-CLP Regulation, UK SI 2019/720, and UK SI 2020/1567) Corrosive to metals, Category 1 H290: May be corrosive to metals. Acute toxicity, Category 4 H302: Harmful if swallowed. Acute toxicity, Category 4 H332: Harmful if inhaled. Acute toxicity, Category 4 H312: Harmful in contact with skin. Skin corrosion, Category 1 H314: Causes severe skin burns and eye damage. Serious eye damage, Category 1 H318: Causes serious eye damage. Respiratory sensitisation, Category 1 H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled. Skin sensitisation, Category 1 H317: May cause an allergic skin reaction. Germ cell mutagenicity, Category 1B H340: May cause genetic defects. Carcinogenicity, Category 1A H350: May cause cancer. Reproductive toxicity, Category 2 H361f: Suspected of damaging fertility. Specific target organ toxicity - single H335: May cause respiratory irritation. exposure, Category 3, Respiratory system Specific target organ toxicity - repeated H373: May cause damage to organs through exposure, Category 2 prolonged or repeated exposure. Long-term (chronic) aquatic hazard, H411: Toxic to aquatic life with long lasting effects. Category 2 2.2 Label elements Labelling (REGULATION (EC) No 1272/2008) as amended by GB-CLP Regulation, UK SI 2019/720, and UK SI 2020/1567) Hazard pictograms : Signal word : Danger Hazard statements : H290 May be corrosive to metals. H302 + H312 + H332 Harmful if swallowed, in contact with skin or if inhaled. H314 Causes severe skin burns and eye damage. H317 May cause an allergic skin reaction. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H335 May cause respiratory irritation. H340 May cause genetic defects. H350 May cause cancer. H361f Suspected of damaging fertility. H373 May cause damage to organs through prolonged or repeated exposure. H411 Toxic to aquatic life with long lasting effects. Precautionary statements : Prevention: P201 Obtain special instructions before use. P260 Do not breathe mist or vapours. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. Response: P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P342 + P311 If experiencing respiratory symptoms: Call a POISON CENTER/ doctor. P391 Collect spillage. Hazardous components which must be listed on the label: Chromium trioxide Additional Labelling Restricted to professional users. 2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. SECTION 3: Composition/information on ingredients 3.2 Mixtures Components Chemical name CAS-No. Classification Concentration EC-No. (% w/w) Index-No. Registration number Chromium trioxide 1333-82-0 Ox. Sol. 1; H271 >= 3 - < 5 215-607-8 Acute Tox. 3; H301 024-001-00-0 Acute Tox. 2; H330 01-2119441306-46 Acute Tox. 2; H310 Skin Corr. 1A; H314 Eye Dam. 1; H318 Resp. Sens. 1; H334 Skin Sens. 1; H317 Muta. 1B; H340