Proteinase K (d-PrK)

Roche Diagnostics Deutschland GmbH

Revision date : 2026-05-23

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GHS08
Health risk rating 5
Safety risk rating 1
Environmental risk rating 1

Note: Ingredients listed on restricted chemical lists

EC/CAS

56-81-5

Name of the chemical

glycerol

Concentration

>=30-<60

General Information

Revision date

2026-05-23

Product name

Proteinase K (d-PrK)

Emergency telephone

+49(0)621-759-2203, +49(0)6131-19240, +496217592890

Icons in SDS

GHS08 M004 M009 M010 M011

Company Information

company name

Roche Diagnostics Deutschland GmbH

e-mail address of the competent person responsible for the Safety Data Sheet

info.dia-sds@roche.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H317, H334

Hazard statements

Code

Statements

H317

May cause an allergic skin reaction

Section 2

SECTION 2: Hazards identification

Classification of the hazardous chemical Respiratory sensitisation Category 1 Skin sensitisation Category 1

Signal word

Danger

Hazard statements

H317 May cause an allergic skin reaction. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Prevention

P261 Avoid breathing mist or vapours. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves. P285 In case of inadequate ventilation wear respiratory protection.

Response

P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P341 IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. P333 + P313 If skin irritation or rash occurs: Get medical advice/ attention. P342 + P311 If experiencing respiratory symptoms: Call a POISON CENTER or doctor/ physician. P363 Wash contaminated clothing before reuse.

Disposal

P501 Dispose of contents/ container to an approved waste disposal plant. SECTION 3: Composition and information of the ingredients of the hazardous chemical

2.1 Classification of the substance or mixture

Respiratory sensitisation : Category 1 Skin sensitisation : Category 1 Label elements Hazard pictograms : Signal word : Danger Hazard statements : H317 May cause an allergic skin reaction. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. Precautionary statements : Prevention: P261 Avoid breathing mist or vapours. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves. P285 In case of inadequate ventilation wear respiratory protection. Response: P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P341 IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. P333 + P313 If skin irritation or rash occurs: Get medical advice/ attention. P342 + P311 If experiencing respiratory symptoms: Call a POISON CENTER or doctor/ physician. P363 Wash contaminated clothing before reuse. Disposal: P501 Dispose of contents/ container to an approved waste disposal plant. SECTION 3: Composition and information of the ingredients of the hazardous chemical Substance / Mixture : Mixture Components Chemical name CAS-No. Concentration (% w/w) Glycerol 56-81-5 >= 30 - < 60 Proteinase K 39450-01-6 >= 1 - < 3 Disodium dihydrogen 139-33-3 < 1 ethylenediaminetetraacetate SECTION 4: First aid measures General advice : Move out of dangerous area. Show this safety data sheet to the doctor in attendance. Do not leave the victim unattended. If inhaled : Call a physician or poison control centre immediately. If unconscious, place in recovery position and seek medical advice. In case of skin contact : If on skin, rinse well with water. In case of eye contact : Flush eyes with water as a precaution. Remove contact lenses. Protect unharmed eye. Keep eye wide open while rinsing. If eye irritation persists, consult a specialist. If swallowed : Keep respiratory tract clear. Do not give milk or alcoholic beverages. Never give anything by mouth to an unconscious person. If symptoms persist, call a physician. Take victim immediately to hospital. Most important symptoms : May cause an allergic skin reaction. and effects, both acute and May cause allergy or asthma symptoms or breathing delayed difficulties if inhaled. Notes to physician

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