Lysis Buffer 1 / Lys 2 / Segme

Roche Diagnostics Deutschland GmbH

Revision date : 2024-10-07

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GHS05 GHS07
Health risk rating 4
Safety risk rating 4
Environmental risk rating 3

General Information

Revision date

2024-10-07

Product name

Lysis Buffer 1 / Lys 2 / Segme

1.2.1 Relevant identified uses

Laboratory chemicals, Refer to product literature for further details

Emergency telephone

+49(0)621-759-2203, +49(0)6131-19240

Icons in SDS

GHS05 GHS07 M004 M009 M010 M011 M013

Company Information

company name

Roche Diagnostics Deutschland GmbH

e-mail address of the competent person responsible for the Safety Data Sheet

info.dia-sds@roche.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H302, H314, H318, H412

Hazard statements

Code

Statements

H302

Harmful if swallowed

Section 2

SECTION 2: Hazards identification

Regulation (EC) No. 1272/2008 Classification of the substance or mixture

Signal word

Danger

Hazard statements

H302 Harmful if swallowed. H314 Causes severe skin burns and eye damage. H412 Harmful to aquatic life with long lasting effects.

Supplemental label elements

EUH032 Contact with acids liberates very toxic gas. EUH071 Corrosive to the respiratory tract.

Prevention

P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.

Response

P301 + P330 + P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a

Hazardous Ingredients

Guanidinium thiocyanate Polidocanol 1,4-Dithiothreitol (DTT)

Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher

2.1 Classification of the substance or mixture

Classification (REGULATION (EC) No 1272/2008) as amended by GB-CLP Regulation, UK SI 2019/720, and UK SI 2020/1567) Acute toxicity, Category 4 H302: Harmful if swallowed. Skin corrosion, Sub-category 1C H314: Causes severe skin burns and eye damage. Serious eye damage, Category 1 H318: Causes serious eye damage. Long-term (chronic) aquatic hazard, H412: Harmful to aquatic life with long lasting Category 3 effects. Lysis Buffer 1 / Lys 2 / Segme 3 2.2 Label elements Labelling (REGULATION (EC) No 1272/2008) as amended by GB-CLP Regulation, UK SI 2019/720, and UK SI 2020/1567) Hazard pictograms : Signal word : Danger Hazard statements : H302 Harmful if swallowed. H314 Causes severe skin burns and eye damage. H412 Harmful to aquatic life with long lasting effects. Supplemental Hazard : EUH032 Contact with acids liberates very toxic gas. Statements EUH071 Corrosive to the respiratory tract. Precautionary statements : Prevention: P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. Response: P301 + P330 + P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor. Hazardous components which must be listed on the label: Guanidinium thiocyanate Polidocanol 1,4-Dithiothreitol (DTT) 2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. SECTION 3: Composition/information on ingredients 3.2 Mixtures Lysis Buffer 1 / Lys 2 / Segme 4 Components Chemical name CAS-No. Classification Concentration EC-No. (% w/w) Index-No. Registration number Guanidinium thiocyanate 593-84-0 Acute Tox. 4; H302 >= 30 - < 50 209-812-1 Acute Tox. 4; H332 615-004-00-3 Acute Tox. 4; H312 01-2120735072-65 Skin Corr. 1C; H314 Eye Dam. 1; H318 Aquatic Chronic 3; H412 Poly(oxy-1,2-ethanediyl), α-dodecyl- 9002-92-0

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