Note: Ingredients listed on restricted chemical lists
EC/CAS
233-140-8/10043-52-4
Name of the chemical
calcium chloride
Concentration
>=10,0-<
General Information
Revision date
2026-05-27
Product name
Endpoproteinase Arg-C
1.2.1 Relevant identified uses
Laboratory chemicals, Refer to product literature for further details
Emergency telephone
+49(0)621-759-2203, +49(0)6131-19240
Icons in SDS
Company Information
company name
Roche Diagnostics Deutschland GmbH
e-mail address of the competent person responsible for the Safety Data Sheet
info.dia-sds@roche.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H319, H334, H373
Hazard statements
Code
Statements
H319
Causes serious eye irritation
Section 2
SECTION 2: Hazards identification
Regulation (EC) No. 1272/2008 Classification of the substance or mixture
Signal word
Danger
Hazard statements
H319 Causes serious eye irritation. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H373 May cause damage to organs through prolonged or repeated exposure.
Prevention
P260 Do not breathe dust. P280 Wear eye protection/ face protection. P284 Wear respiratory protection.
Response
P304 + P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P337 + P313 If eye irritation persists: Get medical advice/ attention. P342 + P311 If experiencing respiratory symptoms: Call a POISON CENTER/ doctor.
Hazardous Ingredients
139-33-3 disodium dihydrogen ethylenediaminetetraacetate 82047-85-6 Proteinase, submandibular gland serine, A
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
ECOLOGICAL INFORMATION
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
TOXICOLOGICAL INFORMATION
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
2.1 Classification of the substance or mixture
Classification (REGULATION (EC) No 1272/2008) Eye irritation, Category 2 H319: Causes serious eye irritation. Respiratory sensitisation, Category 1 H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled. Specific target organ toxicity - repeated H373: May cause damage to organs through exposure, Category 2 prolonged or repeated exposure. 2.2 Label elements Labelling (REGULATION (EC) No 1272/2008) Hazard pictograms : Signal word : Danger Hazard statements : H319 Causes serious eye irritation. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H373 May cause damage to organs through prolonged or repeated exposure. Precautionary statements : Prevention: P260 Do not breathe dust. P280 Wear eye protection/ face protection. P284 Wear respiratory protection. Response: P304 + P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P337 + P313 If eye irritation persists: Get medical advice/ attention. P342 + P311 If experiencing respiratory symptoms: Call a POISON CENTER/ doctor. Hazardous components which must be listed on the label: 139-33-3 disodium dihydrogen ethylenediaminetetraacetate 82047-85-6 Proteinase, submandibular gland serine, A 2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. Ecological information: The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. Toxicological information: The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. SECTION 3: Composition/information on ingredients 3.2 Mixtures Components Chemical name CAS-No. Classification Concentration EC-No.