infotec Devloper Yellow ISC 2525/3030

Potential health effects

There are no significant hazards expected with intended use.

Environmental effects

There are no significant hazards expected with intended use.

Other physicochemical hazards

There are no significant hazards expected with intended use. Specific Hazards Dust explosion (like most finely grained organic powders) －1－ Main Symptoms Acute Inhalation Toxicity Exposure to excessive amount of dust may cause physical irritation to respiratory tract . Acute Oral Toxicity Low acute toxicity in animal experiment. Acute Eye Irritation May cause slight transient irritation. Acute Skin Irritation May be non-irritant. Sensitization From test no apparent significant hazards are expected . (Only few cases reported on incidental allergy-related conjunctivitis or dermatitis.)

Potential chronic health

Slight pulmonary fibrosis has been reported in rats upon chronic inhalation exposure to a toner at 4mg/m3 every day for 2 years. No pulmonary change was found at 1mg/m3. These findings show that exposure to excessive amounts of powder may cause damage to lungs. However, normal use and handling of this product as intended, does not result in inhalation of excessive amounts of powder. Carcinogenicity Titanium dioxide contained in this product is classified to Group 2B of IARC as the result of inhalation test in use of rat. But oral/skin test does not show carcinogenicity. In the animal experiment with very high concentration of titanium dioxide (excessive burden of rat’s lungs clearance mechanism (overload phenomenon)), the rat alone showed lung tumor. Under a normal use practice, the concentration should be far lower than the above ; and it is assumed that there is no such use. Also, relation between respiratory disease and work exposure of titanium dioxide is not observed with epidemiological survey. The Classification of The Chemical Product This preparation is not classified as dangerous according to Directive 1999/45/EC.