ADDOLINK TT 44C/528S

SECTION 2: Hazards identification

EMERGENCY OVERVIEW DANGER! Non-regulated. Color White to Yellowish Form Solid Powder Odor Aromatic, Slight Odor Causes respiratory tract irritation. May cause allergic respiratory reaction. Harmful if inhaled. Respiratory sensitizer. Causes skin irritation. May cause allergic skin reaction. Skin sensitizer. Causes eye irritation. Harmful if swallowed. May cause lung damage. Ground containers and equipment before transferring to avoid static sparks. Vapors or mist may be a fire and explosion hazard when exposed to high temperature or ignition. Use cold water spray to cool fire-exposed containers to minimize the risk of rupture. Reaction with water or foam can be vigorous. Use water as fog or mist; solid streams may spread fire. Toxic gases/fumes are given off during burning or thermal decomposition. Closed container may explode under extreme heat.

Principle Routes of Exposure

Inhalation, Skin Contact HUMAN EFFECTS AND SYMPTOMS OF OVEREXPOSURE Inhalation Hazards Acute Inhalation Hazards: TDI dust, vapors or mist at concentrations above the TLV can irritate (burning sensation) the mucous membranes in the respiratory tract (nose, throat, lungs) causing runny nose, sore throat, coughing, chest discomfort, shortness of breath and reduced lung function (breathing obstruction). Persons with a preexisting, nonspecific bronchial hyperreactivity can respond to concentrations below the exposure limit with similar symptoms as well as asthma attack. Exposure to high vapor concentrations may lead to bronchitis, bronchial spasm and pulmonary edema (fluid in lungs). These effects are usually reversible. Chemical or hypersensitive pneumonitis, with flu-like symptoms (e.g., fever, chills) has also been reported. These symptoms can be delayed up to several hours after exposure. Chronic Inhalation Hazards: As a result of previous repeated overexposures or a single large dose, certain individuals may develop isocyanate sensitization (chemical asthma) which will cause them to react to a later exposure to isocyanate at levels well below the suggested exposure limit. These symptoms, which can include chest tightness, wheezing, cough, shortness of breath or asthma attack, could be immediate or delayed (up to several hours after exposure). Similar to many non-specific asthmatic responses, there are reports that once sensitized an individual can experience these symptoms upon exposure to dust, cold air or other irritants. This increased lung sensitivity can persist Material Name: ADDOLINK TT 44C/528S Article Number: 2255514 2 of 13 for weeks and in severe cases for several years. Chronic overexposure to isocyanate has also been reported to cause lung damage (including decrease in lung function) which may be permanent. Sensitization can either be temporary or permanent. There has been a preliminary report on a possible new finding on sensitization. A TDI manufacturer, BASF, reported that 15 out of 269 TDI production employees developed asthma-like reactions attributed to TDI exposure. They indicated that the number of employees experiencing these reactions (about 1% per year) is not unusual. What is unusual is that 7 out of 15 individuals had experienced prior exposures to respiratory irritants, such as phosgene and chlorine, and this may have led to an increased risk of sensitization to TDI. Chlorine and phosgene are used in the synthesis of TDI and are not expected to be present in user facilities.* *Reference: BASF 8(e) Notification to EPA dated February 3, 1998. Skin Hazards Acute Skin Hazards: Isocyanates react with skin protein and moisture and can cause irritation which may include the following symptoms: reddening, swelling, rash, scaling, or blistering. Cured material is difficult to remove. Chronic Skin Hazards: Prolonged contact can cause reddening, swelling, rash, scaling, blistering, and in some cases, skin sensitization. Individuals who have skin sensitization can develop these symptoms from contact with liquid or vapors. Eye Hazards Acute Eye Hazards: Dust, liquid, aerosols or vapors are severely irritating and can cause pain, tearing, reddening and swelling. If left untreated, corneal damage can occur and injury is slow to heal. However, damage is usually reversible. See First Aid Section for treatment. Chronic Eye Hazards: Repeated and/or prolonged exposures may result in adverse eye effects such as conjunctivitis or corneal damage. Ingestion Hazards Acute Ingestion Hazards: Can result in irritation and corrosive action in the mouth, stomach tissue and digestive tract. Symptoms can include sore throat, abdominal pain, nausea, vomiting and diarrhea. Chronic Ingestion Hazards: None reported for the product. Carcinogenic Effects: No carcinogenic activity was observed in lifetime inhalation studies in rats and mice (International Isocyanate Institute). Carcinogenic Components: NTP: 2,4-Toluene Diisocyanate Monomer (TDI): Classified as an NTP Anticipated Human Carcinogen - "Substances or groups of substances that may reasonably be anticipated to be carcinogens." IARC: 2,4-Toluene Diisocyanate Monomer (TDI): Classified as IARC Possible Human Carcinogen (Group 2B) - "The chemical or group of chemicals is possibly carcinogenic for humans." OSHA: 2,4-Toluene Diisocyanate Monomer (TDI): Not regulated Material Name: ADDOLINK TT 44C/528S Article Number: 2255514 3 of 13

Medical Conditions Generally Aggravated by Exposure

May aggravate asthma., May aggravate respiratory disorders., May aggravate skin conditions., May aggravate skin allergies.

Potential health effects

PRODUCT AS A WHOLE: Mechanical irritation can be produced Postnote: if this product is introduced into the eye. Small quantities of isocyanates (TDI) may be released when drums are opened for the first time. Air sampling on similar products has shown these levels to be below the suggested exposure limit. If this product is heated at temperatures greater than 212 F (100 C), slow decomposition takes place in which TDI is liberated. If this material is heated above 350 F (177 C) (i.e. during thermal processing), a significant increase in TDI vapors may be generated. Results from air-sampling on similar products show that TDI concentrations which exceed the suggested exposure limit may be present during thermal processing.