Anti-Goat HRP-DAB Cell & Tissue Staining Kit

Hazard statements (CLP)

H341, H350, H412

Code

Statements

H341

Suspected of causing genetic defects

2.1 Classification of the substance or mixture

Regulation (EC) No 1272/2008 [EU-GHS/CLP] 3,3’-Diaminobenzidine (DAB) Chromogen Carcinogenicity, 1B Germ Cell Mutagenicity, 2 Regulation (EC) No. 1272/2008 [CLP/GHS] Sodium Azide (0.1%) Aquatic Chronic 3

Signal word

DANGER none

Hazard statements

H341 Suspected of causing genetic defects. H350 May cause cancer H412 Harmful to aquatic life with long lasting effects

Precautionary statements

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P280: Wear protective gloves/protective clothing/eye protection/face protection. P273 Avoid release to the environment

Response

P308 + P313 IF exposed or concerned Get medical advice/attention  Special Hazards: N/A 

EU Classification

Directives 67/548/EEC or 1999/45/EC T Toxic, Xi Irritant Directive 67/548/EEC Xn Harmful

R-phrase(s)

R45 May cause cancer. R68 Possible risk of irreversible effects. R36-Irritating to eyes, R37-Irritating to respiratory system, R38-Irritating to skin. R45 May cause cancer. R68 Possible risk of irreversible effects. R36-Irritating to eyes, R37-Irritating to respiratory system, R38-Irritating to skin. R22 Harmful if swallowed. R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

S-phrase(s)

S45 In case of accident or if you feel unwell, seek medical advice immediately (show label where possible). S53 Avoid exposure – obtain special instructions before use. S26, In case of contact with eyes, rinse immediately with plenty of water and see medical advice.  Special Hazards: none. 3. Information on Ingredients:  Description: 3,3’Diaminobenzidine (DAB) Chromogen S45 In case of accident or if you feel unwell, seek medical advice immediately (show label where possible). S53 Avoid exposure – obtain special instructions before use. S26, In case of contact with eyes, rinse immediately with plenty of water and see medical advice.  Notice to reader: To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.

Contains

CAS No. EC-No. Index-No. 3,3’ Diaminobenzidine 91-95-2 202-110-6 612-239-00-3 <5% Hydrochloric Acid 7647-01-0 231-595-7 017-002-01-X <5% (Not a hazardous substance at this concentration) 4. First Aid Measures:  After inhalation: Move person into fresh air. If not breathing, give artificial respiration. Consult a physician.  After skin contact: Wash off with soap and plenty of water. Take victim immediately to a hospital. Consult a physician.  After eye contact: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. Show this MSDS.  After swallowing: Never give anything by mouth to an unconscious person. Rinse mouth with water. Call a physician. Show this MSDS.  Most important symptoms and effects, both acute and delayed: Unknown  Indication of any immediate medical attention and special treatment needed: No data available 5. Fire Fighting Measures:  Suitable extinguishing agents: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.  Special hazards arising from the substance or mixture: Carbon oxides, nitrogen oxides.  Protective equipment: Wear self contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Further information

no data available 6. Accidental Release Measures:  Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Ensure adequate ventilation. Avoid dust formation, Avoid breathing vapors, mist, dust or gas. Evacuate personnel to safe areas.  Environmental precautions: Do not let product enter drains.  Methods and materials for containment and cleaning up: Pick up and arrange disposal without creating dust. Sweep up and shovel. Absorb spill with inert material, then place in a suitable container. Contain spillage, and then collect for disposal according to local regulations. 7. Handling and Storage:  Precautions for safe handling: Avoid contact with eyes and skin. Avoid formation of dust or aerosols. Obtain special instructions before use. Provide adequate exhaust ventilation at places where dust is formed.  Conditions for safe storage, including incompatibilities: Keep container tightly closed and store in a well-ventilated place. Store locked up. Light sensitive. 8. Exposure Controls and Personal Protection:  Control parameters: Contains no substances with known exposure limits.  Appropriate engineering controls: Wear protective gloves/protective clothing/eye protection/face protection. Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling product. Personal Protective Equipment: Eye and Face Protection: Safety goggles. Face shield. Skin Protection: Handle with gloves. Gloves must be inspected prior to use. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Body Protection: Impervious clothing. Choose body protection according to the amount and concentration of the dangerous substance at the work place. Respiratory Protection: Where risk assessment shows air-purifying respirators are appropriate use full-face respirator. 9. Physical and Chemical Properties:  Appearance: Liquid Upper/lower flammability or explosive limits: Not available  Odor: Not available Vapor density : Not available  Odor threshold: Not available Vapor pressure: Not available  pH: Not available Relative density: Not available  Melting point/freezing point: Not available Boiling point/Boiling range: Not available Partition coefficient noctanol/water Not available Auto igniting: Not available  Flash point: Not available Decomposition temperature: Not available  Water solubility: Not available Viscosity: Not available  Evaporation rate: Not available  Flammability (solid, gas): Not available 10. Stability and Reactivity:  Reactivity: No data available  Chemical Stability: No data available  Possibility of hazardous reactions: No data available  Conditions to avoid: Light  Incompatible materials: Strong oxidizing agents.  Hazardous decomposition products: No data available RTECS DV8750000

TOXICOLOGICAL INFORMATION

Acute toxicity: Rat oral – LD50 = 3,000 mg/kg; mouse oral – LD50 = 1834 mg/kg  Skin corrosion/irritation: Can cause burns of the skin and mucous membranes.  Serious eye damage/irritation: Can cause burns, reduced vision or blindness.  Respiratory or skin sensitization: no data available  Germ cell mutagenicity: Mutagenic effects. Carcinogenicity Rat – oral tumorigenic, skin and appendages  Reproductive toxicity: no data available.  Specific target organ toxicity (STOT) -single exposure: no data available  Specific target organ toxicity (STOT) -repeated exposure: no data available.

Aspiration hazard

Can cause severe burns. Causes respiratory tract irritation  Information on likely routes of exposure: Routes of entry anticipated; oral, dermal, inhalation.  Symptoms related to the physical, chemical and toxicological characteristics: Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. Ingestion: May be harmful if swallowed. Skin contact: May be harmful if absorbed through skin. May cause skin irritation. Eye contact: May cause eye irritation.  Delayed and immediate effects and also chronic effects from short and long term exposure: no data available.  Effects of chronic exposure: no data available  Numerical measures of toxicity: no data available

ECOLOGICAL INFORMATION

Ecotoxicity: no data available.  Biodegradability: no data available  Bioaccumulative potential: no data available.  Mobility in soil: no data available.

Other hazards

no data available

Disposal

Considerations  Disposal methods: Dispose of waste in accordance to applicable national, regional, or local regulations.  Contaminated packaging: Dispose in the same manner as unused product.  Special precautions: Dispose of small amounts of spilled material as described in section 6. Large spills must be dealt with separately by qualified disposal personnel. Avoid dispersal of spilt material to soil, waterways, drains and sewers. 14. Transport Information:

UN Number

None DOT regulations

Hazard categories

None  Land transport ADR/RID (cross-border): Not regulated.  Maritime transport IMDG: Not regulated.  Marine pollutant: No  Air transport ICAO-TI and IATA-DGR: Not regulated.  Transport/Additional information: Not dangerous according to the above specifications. 15. Regulations:  US Federal and State Regulations TSCA (Toxic Substances Control Act): 3,3’ Diaminobenzidine and Hydrochloric acid are listed. SARA 313: 3,3’ Diaminobenzidine is not listed. Hydrochloric acid (acid aerosol) is listed. SARA 311/312 Hazards 3,3’ Diaminobenzidine

Health hazards

Hydrochloric acid Acute Health Hazard CERCLA Reportable Quantity 3,3’ Diaminobenzidine is not listed. Hydrochloric acid 5,000 lbs California Proposition 65: 3,3’ Diaminobenzidine and Hydrochloric acid are not listed on California’s listing of known or potential carcinogens.

Hazard pictograms

none

Principle Routes of Exposure

Inhalation; ingestion or skin IF EXPOSED OR CONCERNED: Get medical advice/attention.

2.3 Other hazards

none