Note: Ingredients listed on restricted chemical lists
EC/CAS
67-68-5
Name of the chemical
dimethyl sulphoxide
Concentration
75-100%
General Information
Revision date
2026-05-01
Product name
HaloTag Ligand
Emergency telephone
1-800-424-9300, +1 703-527-3887
Icons in SDS
Company Information
company name
Promega Corporation
e-mail address of the competent person responsible for the Safety Data Sheet
productstewardship@promega.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H227, H312, H317, H334
Hazard statements
Code
Statements
H227
Combustible liquid
Section 2
SECTION 2: Hazards identification
OSHA Hazards Classification of the substance or mixture GHS08 Health hazard Sensitization - Respiratory 1 H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled GHS07 Acute Toxicity - Dermal 4 H312 Harmful in contact with skin Sensitization - Skin 1 H317 May cause an allergic skin reaction Flammable liquids 4 H227 Combustible liquid
2.2 Label elements
The product is classified and labeled according to the Globally Harmonized System (GHS)
Hazard pictograms
GHS07 GHS08
Signal word
Danger (Contd. on page 2) US
Hazardous Ingredients
dimethyl sulfoxide HaloTag® Succinimidyl Ester (O4) Ligand
Hazard statements
Combustible liquid. Harmful in contact with skin. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.
Precautionary statements
Keep away from flames and hot surfaces. – No smoking. Avoid breathing dust/fume/gas/mist/vapors/spray Contaminated work clothing must not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. [In case of inadequate ventilation] wear respiratory protection. If on skin: Wash with plenty of water. If inhaled: If breathing is difficult, remove person to fresh air and keep comfortable for breathing. Call a poison center/doctor if you feel unwell. Take off contaminated clothing and wash it before reuse. If skin irritation or rash occurs: Get medical advice/attention. If experiencing respiratory symptoms: Call a poison center/doctor. Wash contaminated clothing before reuse. In case of fire: Use CO2, powder or water spray to extinguish. Store in a well-ventilated place. Keep cool. Dispose of contents/container in accordance with local/regional/national/international regulations.
Classification system
NFPA ratings (scale 0 - 4) Health = 1 Fire = 2 Reactivity = 0 HMIS-ratings (scale 0 - 4) Health = *1 Fire = 2 Reactivity = 0
PBT Substances
Not applicable
vPvB Substances
Not applicable US (Contd. on page 3) *
2.1 Classification of the substance or mixture
GHS08 Health hazard Sensitization - Respiratory 1 H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. GHS07 Acute Toxicity - Dermal 4 H312 Harmful in contact with skin. Sensitization - Skin 1 H317 May cause an allergic skin reaction. Flammable liquids 4 H227 Combustible liquid. Label elements GHS label elements The product is classified and labeled according to the Globally Harmonized System (GHS). Hazard pictograms GHS07 GHS08 Signal word Danger (Contd. on page 2) US