Cell Lysis Buffer

Promega Corporation

Revision date : 2025-12-20

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GHS08 GHS07
Health risk rating 4
Safety risk rating 1
Environmental risk rating 1

Note: Ingredients listed on restricted chemical lists

EC/CAS

50-01-1

Name of the chemical

Guanidinium chloride

Concentration

15-40%

Listed in

EC/CAS

57-13-6

Name of the chemical

urea

Concentration

15-40%

General Information

Version

20.0

Revision date

2025-12-20

Product name

Cell Lysis Buffer

Emergency telephone

1-800-424-9300, +1 703-527-3887

Icons in SDS

GHS07 GHS08 M004 M009 M010 M011

Company Information

company name

Promega Corporation

e-mail address of the competent person responsible for the Safety Data Sheet

productstewardship@promega.com

GHS Information

Signal word

Warning

Hazard Codes

Hazard statements (CLP)

H302, H315, H319, H373

Hazard statements

Code

Statements

H302

Harmful if swallowed

Section 2

SECTION 2: Hazards identification

NFPA Rating Classification of the substance or mixture GHS08 Health hazard Specific target organ toxicity (repeated exposure) – H373 May cause damage to the respiratory tract Category 2 through prolonged or repeated exposure GHS07 Acute Toxicity (Oral) - Category 4 H302 Harmful if swallowed Skin Irritation - Category 2 H315 Causes skin irritation Eye damage/irritation – Category 2A H319 Causes serious eye irritation

2.2 Label elements

The product is classified and labeled according to the Globally Harmonized System (GHS)

Hazard pictograms

GHS07 GHS08

Hazardous Ingredients

guanidinium chloride disodium dihydrogenethylenediaminetetraacetate sodium dodecyl sulphate

Hazard statements

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause damage to the respiratory tract through prolonged or repeated exposure.

Precautionary statements

Do not breathe dust/fume/gas/mist/vapours/spray. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Wear protective gloves / eye protection / face protection. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. IF ON SKIN: Wash with plenty of water. Specific treatment (see on this label). IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Get medical advice/attention if you feel unwell. Rinse mouth. Take off contaminated clothing and wash it before reuse. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Get medical advice/attention. Dispose of contents/container in accordance with local/regional/national/international regulations. Information pertaining to particular dangers for man and environment

Classification system

NFPA ratings (scale 0 - 4) Health = 2 Fire = 0 Reactivity = 0 HMIS-ratings (scale 0 - 4) Health = 2 Fire = 0 Reactivity = 0

Other hazards

None Known *

2.1 Classification of the substance or mixture

GHS08 Health hazard Specific target organ toxicity (repeated exposure) – H373 May cause damage to the respiratory tract Category 2 through prolonged or repeated exposure. GHS07 Acute Toxicity (Oral) - Category 4 H302 Harmful if swallowed. Skin Irritation - Category 2 H315 Causes skin irritation. Eye damage/irritation – Category 2A H319 Causes serious eye irritation. Label elements GHS label elements The product is classified and labeled according to the Globally Harmonized System (GHS). Hazard pictograms GHS07 GHS08

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