Note: Ingredients listed on restricted chemical lists
EC/CAS
79-16-3
Name of the chemical
Acetamide, N-methyl
Concentration
10-30%
General Information
Version
13.0
Revision date
2025-12-18
Product name
Binding Buffer (BBC)
Emergency telephone
1-800-424-9300, +1 703-527-3887
Icons in SDS
Company Information
company name
Promega Corporation
e-mail address of the competent person responsible for the Safety Data Sheet
productstewardship@promega.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H302, H314, H317, H318, H332, H360
Hazard statements
Code
Statements
H302
Harmful if swallowed
Section 2
SECTION 2: Hazards identification
NFPA Rating Classification of the substance or mixture GHS08 Health hazard Reproductive Toxicity - Category 1B H360 May damage fertility or the unborn child GHS05 Corrosion Skin Corrosion - Category 1B H314 Causes severe skin burns and eye damage Eye damage/irritation – Category 1 H318 Causes serious eye damage GHS07 Acute Toxicity (Oral) - Category 4 H302 Harmful if swallowed Acute Toxicity (Inhalation) - Category 4 H332 Harmful if inhaled Sensitization - skin – Category 1 H317 May cause an allergic skin reaction
2.2 Label elements
The product is classified and labeled according to the Globally Harmonized System (GHS) (Contd. on page 2) CA (Contd. of page 1)
Hazard pictograms
GHS05 GHS07 GHS08
Signal word
Danger
Hazardous Ingredients
guanidinium thiocyanate N-methylacetamide 3-mercaptopropane-1,2-diol
Hazard statements
Harmful if swallowed or if inhaled. Causes severe skin burns and eye damage. May cause an allergic skin reaction. May damage fertility or the unborn child.
Precautionary statements
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not breathe dust or mists. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection/hearing protection. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER/doctor. IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower]. IF INHALED: Remove person to fresh air and keep comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Specific treatment (see on this label). Take off contaminated clothing and wash it before reuse. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations. Information pertaining to particular dangers for man and environment
Classification system
NFPA ratings (scale 0 - 4) Health = 3 Fire = 0 Reactivity = 0 HMIS-ratings (scale 0 - 4) Health = *3 Fire = 0 Reactivity = 0
2.3 Other hazards
Product has been observed to have sensitizing effects. (Contd. on page 3) CA (Contd. of page 2) None Known
2.1 Classification of the substance or mixture
GHS08 Health hazard Reproductive Toxicity - Category 1B H360 May damage fertility or the unborn child. GHS05 Corrosion Skin Corrosion - Category 1B H314 Causes severe skin burns and eye damage. Eye damage/irritation – Category 1 H318 Causes serious eye damage. GHS07 Acute Toxicity (Oral) - Category 4 H302 Harmful if swallowed. Acute Toxicity (Inhalation) - Category 4 H332 Harmful if inhaled. Sensitization - skin – Category 1 H317 May cause an allergic skin reaction.