SUPER

Hazard statements (CLP)

H302, H313, H315, H317, H318, H319, H335, H341, H351, H400

Code

Statements

H302

Harmful if swallowed

2.1 Classification of the substance or mixture

Classified as dangerous according to the criteria of

Hazard statements

Skin Irrit. category 2 H315: Causes skin irritation. Eye Irrit. category 2 H313: Causes serious eye irritation. STOT SE category 3 H335: May cause respiratory irritation. H315 Causes skin irritati on. H319 Causes serious eye irritati on. H335, May cause respiratory irritati on.

Contains

ethyl 2-cyanoacrylate

Signal word

Warning

Precautionary statements

P101 If medical advice is needed, have product container or label at hand. P102 Keep out of reach of children. P280 Wear protective gloves, protective clothing and eye protection/face protection. P271 Use only outdoors or ina well-venti lated area. P264 Wash hands thoroughly after handling. Created by: Brandweerinformatiecentrum voor gevaarlijke stoffen vzw (BIG) Publication date 2000-09-22 Technische Schoolstraat 43 A, B-2440 Geel 134-16433-702-en Date of revision 2020-07-09 http://Awww.big.be BIG vzw Reason for revision: 3,2; 4; 9; 15 SUPER P304 + P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P405 Store locked up. PSOL Dispose of contents/cantainer in accordance with local/regional/national/international regulation. Keep away from naked flames/heat. 10.5. Incompatible materials (strong) acids, oxidizing agents, water/moisture. 10.6. Hazardous decomposition products At very high temperature release of toxic/combustible gases/vapours (hydrogen cyanide). On burning release of toxic and corrosive gases/vapours (nitrous vapours, carbon monoxide - carbon dioxide). Reason for revision: 3,2; 4; 9; 15 Publication date 2000-09-22 Date of revision 2020-07-09 SUPER 11.1. Information on toxicological effects 11.1.1 Test results No (test}data on the mixture available Judgement is based on the relevant ingredients ethyl! 2-cyanoacrylate

Additional information

EUH202 Cyanoacrylate. Danger. Bonds skin and eyes in seconds. Keep out of the reach of children.

2.3 Other hazards

No other hazards known 3.1. Substances Not applicable 3.2. Mixtures Name . 7 cheno Conc. (C)}

EU Classification

CLP |Nate REACH Registration No

Remarks

ECNo ethyl 2-cyanoacrylate 7085-85-0 88%<C<99% [Skin Irrit. 2; H315 {1})(2}(8}(10) Constituent 01-2119527766-29 230-391-5 Eye Irrit. 2; H319 ISTOT SE 3; H335 1,4-dihydroxybenzene 123-31-9 C<0.1% Muta. 2; H341 {1)(21(9} Constituent 01-2119524016-51 204-617-838 Care. 2; H351 Skin Sens. 1; H317 Acute Tox. 4; H302 Eye Dam. 1; H318 Aquatic Acute 1; H400 {1} For H-statements in full: see heading 16 {2} Substance with a Community workplace exposure limit {8} Specific cancentration limits, see heading 16 {9} M-factor, see heading 16 {10} Subject to restrictions of Annex XVII of DNEL Long-term systemic effects inhalation 9.25 mg/m? Long-term local effects inhalation 9.25 mg/m? L4&-dihydroxybenzene Effect level (DNEL/DMEL) Type Value DNEL Long-term systemic effects inhalation 2.1 mg/m? Long-term systemic effects dermal 3.33 mg/kg bw/day DNEL/DMEL - General population ethyl 2-cyanoacrylate Effect level (DNEL/DMEL) Type Value DNEL Long-term systemic effects inhalation 9.25 mg/m? Long-term local effects inhalation 9.25 mg/m? 14-dihydroxybenzene Effect level (DNEL/DMEL) Type Value DNEL Long-term systemic effects inhalation 1.05 mg/m? Long-term systemic effects dermal 1.66 mg/kg bw/day Long-term systemic effects oral 0.6 mg/kg bw/day PNEC 1,4-dihydroxybenzene Compartments Value Fresh water 0.57 peg/l Marine water 0.057 pg/l Fresh water (intermittent releases} 1.34 ye/l STP 0.71 mg/l Fresh water sediment 4.9 pg/kg sediment dw Marine water sediment 0.49 pg/kg sediment dw Soil 0.64 pg/kg soil dw 8.1.5 Control banding If applicable and available it will be listed below. 8.2. Exposure controls The information in this section is a general description. If applicable and available, exposure scenarios are att ached in annex. Always use the relevant exposure scenarios that correspond to your identified use. 8.2.1 Appropriate engineering controls Keep away from naked flames/heat. Measure the concentration in the air regularly. Carry operations in the open/under local exhaust/ventilation or with respiratory protection. Reason for revision: 3,2; 4; 9; 15 Publication date 2000-09-22 Date of revision 2020-07-09 SUPER 8.2.2 Individual protection measures, such as personal protective equipment Observe normal hygiene standards. Do not eat, drink or smoke during work. a) Respiratory protection Full face mask with filter type A at conc. in air > exposure limit. 'b} Hand protection: Protecti ve gloves against chemicals (EN 374). Materials Measured Thickness Protection index breakthrough time nitrile rubber > 480 minutes O.1mm Class 6 ¢) Eye protection: Face shield {EN 166). cd) Skin protection Protective clothing (EN 14605 or EN 13034). 8.2.3 Environmental exposure controls: See headings 6.2, 6.3 and 13 ECTION 9: Physical and chemical properties 9.1. Information on basic physical and chemical properties Physical form Liquid Odour Characteristic odour Odour threshold No data available in the literature Colour Colourless Particle size Not applicable (liquid) Explosion limits No data available in the literature Flammability Nat classified as flammable Log Kow Not applicable (mixture) Dynamic viscosity No data available in the literature Kinematic viscosity No data available in the literature Melting point No data available in the literature Boiling point 150°C Evaporation rate No data available in the literature Relative vapour density No data available in the literature Vapour pressure No data available in the literature Solubility Water ; insoluble Acetone ; soluble Relative density 1.05 Decomposition temperature No data available in the literature Auto-ignition temperature 500°C Flash point 87°C Explosive properties No chemical group associated with explosive properties Oxidising properties No chemical group associated with oxidising properties IPH No data available in the literature determination Oral LD50 Equivalent to CECD | > 5000 mg/kg bw Rat (male) Experimental value 423 Skin LD50 Equivalent to CECD |> 2000 mg/kg bw |24h Rabbit (male) Experimental value 402 Inhalation Data waiving 1,4-dihydroxybenzene determination Oral LD50 OECD 401 > 375 mg/kg bw Rat (male / Experimental value female} Dermal LD50 QECD 402 > 2000 mg/kg bw |]24h Rabbit {male / Experimental value female} Inhalation (aerosol) |LDO 27.8 me/l air dh Rat (female) Read-across Conclusion Not classified for acute toxicity Corrosion/irritation SUPER No (test}data on the mixture available Classification is based on the relevant ingredients ethy! 2-cyanoacrylate determination Eye Irritating Equivalent to 72h 24; 48; 72 hours Rabbit Experimental OECD 405 value Skin Slightly irritating Equivalent to 24h 24; 72 hours Rabbit Experimental OECD 404 value Skin Irritating; Annex VI category 2 Inhalation Irritating; Annex VI STOT SE cat.3 Classification of this substance according to Annex VI is debatable as it does not correspond to the conclusion from the test 14-dihydroxybenzene determination Eye Serious eye Annex VI damage; category 1 Skin Not irritating 24h 24 hours Rat Weight of evidence Conclusion Causes skin irritation. Causes serious eye irritation May cause respiratory irritati: Respiratory or skin sensitisation SUPER No (test}data on the mixture available Judgement is based on the relevant ingredients ethyl! 2-cyanoacrylate Negative with metabolic OECD 473 Human lymphocytes No effect Experimental value activation, negative without metabolic activation Negative with metabolic OECD 476 Mouse (lymphoma L5178Y No effect Experimental value activation, negative cells) without metabolic activation 1,4-dihydroxybenzene Result Method Test substrate Effect Value determination Negative with metabolic Equivalent to OECD 471 Bacteria (S.typhimurium} No effect Experimental value activation, negative without metabolic activation Positive Equivalent to OECD 476 Mouse (lymphoma L5178Y Experimental value cells) Mutagenicity (in vivo) SUPER No (test}data on the mixture available Judgement is based on the relevant ingredients 1,4-dihydroxybenzene Result Method Expasure time Test substrate Organ Value determination Positive Equivalent to OECD Mouse (male) Experimental value 483 Negative (Oral (stomach tube}} Equivalent to OECD 10 weeks (5 days / Rat (male} Experimental value 478 week) Conclusion Not classified for mutagenic or genotoxic toxicity SUPER Reason for revision: 3,2; 4; 9; 15 Publication date 2000-09-22 Date of revision 2020-07-09 SUPER No {test}data on the mixture available Judgement is based on the relevant ingredients 1,4-dihydroxybenzene Route of Parameter Method Value Exposure time Species Effect Organ Value exposure determination Oral Dose level Equivalent to 50 mg/kg 65 weeks (5 days / | Rat (male) Tumor Kidney Experimental OECD 453 bw/day week) - 103 weeks formation value (5 days / week) Oral Dose level Equivalent to 225 mg/kg 65 weeks (5 days / | Rat (female) Change in the Blood Experimental OECD 453 bw/day week) - 103 weeks haemogramme/ value (5 days / week) blood

Further information

Absolute density [2050 kg/m? ] ECTION 10: Stability and reactivity 10.1. Reactivity Temperature above flashpoint: higher fire/explosion hazard. 10.2. Chemical stability Unstable on exposure to moisture. Unstable on exposure to air. 10.3. Possibility of hazardous reactions Palymerizes on exposure to water {moisture} and on exposure to temperature rise: pressure rise and possible bursting of container. 10.4. Conditions to avoid

Principle Routes of Exposure

Parameter |Method Value Exposure time Species Value |Parameter |Method Value Exposure time Species Value /Result Method Exposure time Time point Species Value /Result Method Exposure time Time point Species Value [Result Method Exposure time Observation time |Species Value determination |Remark point Skin Not sensitizing Guinea pig Guinea pig (male | Literature study maximisation test f female) Reason for revision: 3,2; 4; 9; 15 Publication date 2000-09-22 Date of revision 2020-07-09 SUPER 1,4-dihydroxybenzene |Result Method Exposure time Observation time Species Value determination |Remark point Skin Sensitizing Equivalent to OECD 3 day(s) Mouse (female) | Experimental value 429 Conclusion Not classified as sensitizing for inhalation Not classified as sensitizing for skin Specific target organ toxi SUPER No (test}data on the mixture available Judgement is based on the relevant ingredients ethyl 2-cyanoacrylate |Parameter |Method Value Organ Effect Exposure time Species Value determination Oral Data waiving Dermal Data waiving Inhalation Data waiving 1 ihydroxybenzene |Parameter |Method Value Organ Effect Exposure time Species Value determination Oral (stomach NOAEL Equivalent to 25 mg/kg No effect 65 weeks (5 days / Rat (male) Experimental tube} OECD 453 bw/day week} - 103 weeks (5 value days / week} Dermal NOAEL Equivalent to 73.9 mg/l - No effect 13 weeks (6h / day, 5 Rat (male / Experimental OECD 411 109.6 mg/l days / week} female} value Inhalation Data waiving Conclusion Not classified for subchronic toxicity Mutagenicity (in vitro) SUPER No (test}data on the mixture available Judgement is based on the relevant ingredients ethyl 2-cyanoacrylate Result Method Test substrate Effect Value determination