Sulfacetamide Sodium & Prednisolone Sodium Phosphate

SECTION 2: Hazards identification

EMERGENCY OVERVIEW Plastic bottle packed in a cardboard box. Clear, colorless to slightly yellow, solution. Contains thimerosal. Decomposition product mercury vapor. Toxic by ingestion. **********************************************************************************************

Health hazards

Carcinogenicity: (NTP) No (IARC) No (OSHA) No Eye: May cause irritation. Repeated or prolonged exposure can cause hypersensitivity and or conjunctivitis in some individuals. This preparation is only for the eyes. It has been shown, though not in humans, that through large doses or prolonged topical administration, glucocorticoids may be systemically adsorbed by pregnant mothers and produce fetal abnormalities. Systematically administered corticosteroids are secreted into breast milk in quantities not likely to have a deleterious effect on the infant. Systemic toxicity reactions include reversible hypothalamic-pituitary-adrenal axis gland suppression, manifestations of Cushing's syndrome, intercranial hypertension, hyperglycemia and glycosuria. Skin: May cause irritation. Repeated or prolonged exposure can cause hypersensitivity in some individuals. Ingestion: May cause irritation. Repeated or prolonged exposure can cause hypersensitivity in some individuals. . Large doses may induce vomiting, diarrhea, adrenal gland suppression, Cushing's syndrome, water retention, electrolyte imbalance and hyper-glycemia. Inhalation: May cause irritation. Evaporation of this product is minimal. Vapor inhalation under controlled conditions does not pose a hazard.

Potential chronic health

Hypersensitivity reactions include rash, itching, photosensitivity, inflammation, drug fever, nervous system effects and headache. Can also cause conjunctivitis. Target Organs: Eyes, skin and central nervous system.

Medical Conditions Generally Aggravated by Exposure

Hypersensitivity (anaphylactic) to Sulfacetamide Sodium, Prednisolone Sodium Phosphate or any of the components of the product. Individuals sensitive to one sulfonamide may be sensitive to another. Persons hypersensitive to furosemide, sulfones, thiazide diuretics, sulfonylureas or carbonic anhydrase inhibitors may be hypersensitive to sulfonamides also. Individuals with dermatitis.