Methotrexate

Hazard statements (CLP)

H301, H315, H319, H341, H360

Code

Statements

H301

Toxic if swallowed

2.1 Classification of the substance or mixture

GHS Classification in accordance with Hazardous Products Regulations (HPR) (SOR/2015-17) Acute toxicity, Oral (Category 3), H301 Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 Germ cell mutagenicity (Category 2), H341 Reproductive toxicity (Category 1B), H360 For the full text of the H-Statements mentioned in this Section, see Section 16.

Signal word

Danger

Hazard statements

H301 Toxic if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H341 Suspected of causing genetic defects. H360 May damage fertility or the unborn child.

Precautionary statements

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P302 + P352 IF ON SKIN: Wash with plenty of water. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 + P364 Take off contaminated clothing and wash it before reuse. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant.

2.3 Other hazards

none