Isobutene

SECTION 2: Hazards identification

Flammability Toxicity 1) Health Body Contact © Flammability Reactivity ©) Chronic 1 2 3 4 Fire Diamond Min Low Moderate High Extreme ANSI Signal Word Danger! Flammable wowewveve Emergency Overview * % % ve Colorless gas. Acute Effects Simple asphyxiant which can displace available oxygen; initial symptoms rapid respiration, air hunger, diminished mental alertness, impaired muscular coordination. Can form explosive mixtures in air. Flammable.

Potential health effects

Target Organs: None reported

Principle Routes of Exposure

inhalation Acute Effects Inhalation: The gas is a simple asphyxiant (precludes access to oxygen) and is harmful if exposure is prolonged and inhalation may cause loss of consciousness. Copyright © 2006 by Genium Group, Inc. Any commercial use or reproduction without the publisher’s permission is prohibited. Judgments as to the suitability of information herein for the purchaser’ s purposes are necessarily the purchaser’s responsibility. Although reasonable care has been taken in the preparation of such information, Genium Group, Inc. extends no warranties, makes no representations, and assumes no responsibility as to the accuracy or suitability of such information for application to the purchaser’s intended purpose or for consequences of its use. Acute effects from inhalation of high concentrations of gas / vapor are pulmonary irritation, including coughing, with nausea; central nervous system depression - characterized by headache and dizziness, increased reaction time, fatigue and loss of coordination. If exposure to highly concentrated atmosphere of gas is prolonged this may lead to narcosis, unconsciousness, even coma, and unless resuscitated, death. Iso-butene is a simple asphyxiant and may have a narcotic action. Material is highly volatile and may quickly form concentrated atmosphere in confined or unventilated area. Vapor is heavier than air and may displace and replace air in breathing zone, acting as a simple asphyxiant. This may happen with little warning of overexposure. Hydrocarbons may sensitize the heart to adrenalin and other circulatory catecholamines; as a result cardiac arrhythmias and ventricular fibrillation may occur. Abrupt collapse may produce traumatic injury. Central nervous system (CNS) depression may be evident early. Symptoms of moderate poisoning may include giddiness, headache, dizziness and nausea. Serious poisonings may result in respiratory depression and may be fatal. The paraffin gases C1-4 are practically non-toxic below their lower flammability limits (18000-50000 ppm). Above this level, incidental effects include CNS depression and irritation but these are reversible upon cessation of the exposure. The C3 and iso-C5 hydrocarbons show increasing narcotic properties; branching of the chain also enhances the effect. The C4 hydrocarbons appear to be more highly neurotoxic than the C3 and C5 members. Several fatalities due to voluntary inhalation of butane have been reported, possibly due to central, respiratory and circulatory effects resulting from anesthesia, laryngeal edema, chemical pneumonia or the combined effects of cardiac toxicity and increased sympathomimetic effects. Inhalation of petroleum gases may produce narcosis, due in part to olefinic impurities. Displacement of oxygen in the air may cyanosis. If present in sufficient quantity these gases may reduce the oxygen level to below 18% producing asphyxiation. Symptoms include rapid respiration, mental dullness, lack of coordination, poor judgement, nausea and vomiting. The onset of cyanosis may lead to unconsciousness and death. Eye: The liquid is highly discomforting and may cause severe cold burns and is capable of causing pain and severe conjunctivitis. Corneal injury may develop, with possible permanent impairment of vision, if not promptly and adequately treated. The gas is regarded as non-irritating to the eyes. Skin: Vaporizing liquid causes rapid cooling and contact may cause cold burns, frostbite.The liquid is discomforting to the skin and may rapidly cause severe cold burns. Bare unprotected skin should not be exposed to this material. There is no evidence of skin absorption but contact may cause frostbite, Ingestion: Overexposure is unlikely in this form. Considered an unlikely route of entry in commercial/industrial environments. The liquid is highly discomforting if swallowed and may cause severe cold burns. Carcinogenicity: NTP - Not listed; IARC - Not listed; OSHA - Not listed; NIOSH - Not listed; ACGIH - Not listed; EPA - Not listed; MAK - Not listed.

Potential chronic health

Chronic overexposure may produce dermatitis