Ethylene Oxide in Nitrogen 0.0001% to 3.6%

SECTION 2: Hazards identification

Emergency Overview: Non-flammable colorless gas with slight sweet odor. Simple Asphyxiant – This product does not contain oxygen and may cause asphyxia if released in a confined area. Maintain oxygen levels above 19.5%. This product contains ethylene oxide, a substance that can cause cancer and has been associated with adverse fetal and reproductive effects in animals. Inhalation of ethylene oxide can cause irritation and affect the lungs and nervous system. Ethylene oxide may undergo hazardous polymerization and explosive decomposition. Contents under pressure. Use and store below 125OF (52O C).

Principle Routes of Exposure

Skin Contact Skin Absorption Eye Contact Inhalation Ingestion Yes No Yes No NorLab, Ethylene Oxide in Nitrogen 0.0001% to 3.6% Material Safety Data Sheet 2530 Page 2 of 6 Continued

Potential health effects

Exposure Limits Irritant Sensitization Yes No Teratogen Reproductive Hazard Mutagen Yes Synergistic Effects None reported Carcinogenicity: NTP: Yes IARC: Yes OSHA: Yes Eye Effects: May cause irritation and conjunctivitis. Contact with rapidly expanding gas near the point of release may cause frostbite. Skin Effects: Ethylene oxide may cause irritation at low concentrations or characteristic burns at higher concentrations. Redness, dermatitis, blisters, edema, burns, and tissue damage may develop. May be absorbed through the skin. Contact with rapidly expanding gas near the point of release may cause frostbite with redness, skin color change to gray or white, and blistering. Ingestion Effects: None known. Ingestion is unlikely as product is a gas at room temperature. Inhalation Effects: May irritate the eyes, nose, throat, and lungs. Low concentrations may cause delayed nausea and vomiting. High concentrations can have a narcotic and possibly neurotoxic effect that can be followed by coughing and vomiting. Irritation of the respiratory passages may lead to pneumonitis and retention of body fluid and swelling in the lungs (edema). Emphysema and bronchitis may occur. Overexposure to ethylene oxide may adversely affect the lungs, liver, kidneys, endocrine system, central nervous system, and blood forming elements. Chronic intoxication has been reported in humans. Ethylene oxide is a human carcinogen. Exposure may cause toxicity to the human reproductive system including spontaneous abortions. Chromosomal aberrations have been detected in ethylene oxide expose workers. The nitrogen balance gas in this product is a non-toxic simple asphyxiant. High concentrations may exclude an adequate supply of oxygen to the lungs. Effects of oxygen deficiency resulting from simple asphyxiants may include: rapid breathing, diminished mental alertness, impaired muscular coordination, faulty judgment, depression of all sensations, emotional instability, and fatigue. As asphyxiation progresses, nausea, vomiting, prostration, and loss of consciousness may result, eventually leading to convulsions, coma, and death. Oxygen deficiency during pregnancy has produced developmental abnormalities in humans and experimental animals.

Medical Conditions Generally Aggravated by Exposure

Irritant effects may aggravate pre-existing eye, skin, and upper respiratory disorders.

Environmental effects

The LC50 for ethylene oxide in the goldfish is 90 mg/L/24 H (modified ASTM D 1345). NFPA Hazard Codes HMIS Hazard Codes Ratings System Health: 1 Health: 1* 0: No Hazard Flammability: 0 Flammability: 0 1: Slight Hazard Instability: 0

Physical hazards

3 2: Moderate Hazard 3: Serious Hazard *Carcinogen 4: Severe Hazard Ratings were assigned in accordance with Compressed Gas Association (CGA) guidelines as published in CGA Pamphlet P-19-2009, CGA Recommended Hazard Ratings for Compressed gases, 3rd Edition. NorLab, Ethylene Oxide in Nitrogen 0.0001% to 3.6% Material Safety Data Sheet 2530 Page 3 of 6