Chrysene

SECTION 2: Hazards identification

Flammability Toxicity (2) Tia Body Contact @ Flammability Reactivity Chronic (0) 1 2 3 Fire Diamond Min Low Moderate High Extreme ANSI Signal Word Caution wowewveve Emergency Overview * % % ve Colorless to white crystals with reddish-blue fluorescence. May be irritating to eyes/skin/respiratory tract. Also causes: may be absorbed through skin. May be cancer-causing in humans. Combustible.

Potential health effects

Target Organs: Eyes, skin, respiratory system

Principle Routes of Exposure

Skin absorption Acute Effects There is no human evidence available for the acute health effects of chrysene alone. There is, however, considerable data indicating that it is carcinogenic in humans. Based on the chemical properties of chrysene, as a polynuclear aromatic hydrocarbon, the following acute effects may occur. Inhalation: May cause irritation. Eye: . May cause irritation. Skin: May cause irritation or be absorbed. Ingestion: None reported. Carcinogenicity: NTP - Not listed; IARC - Group 3, Not classifiable as to carcinogenicity to humans; OSHA - Not listed; NIOSH - Listed as carcinogen; ACGIH - Class A3, Animal carcinogen; EPA - Class B2, Probable human carcinogen based on animal studies; MAK - Class A2, Unmistakably carcinogenic in animal experimentation only. Copyright © 2006 by Genium Group, Inc. Any commercial use or reproduction without the publisher’s permission is prohibited. Judgments as to the suitability of information herein for the purchaser’ s purposes are necessarily the purchaser’s responsibility. Although reasonable care has been taken in the preparation of such information, Genium Group, Inc. extends no warranties, makes no representations, and assumes no responsibility as to the accuracy or suitability of such information for application to the purchaser’s intended purpose or for consequences of its use.

Medical Conditions Generally Aggravated by Exposure

None reported

Potential chronic health

Animal data indicate that chronic exposure to chrysene and other coal tar pitch volatiles probably causes cancer. May also cause respiratory, skin, or eye irritation; cough, bronchitis, photosensitivity, "coal tar warts" (precancerous lesions enhanced by UV light exposure), erythema (skin inflammation), dermal burns, acneiform lesions, hematuria (blood in urine). May alter genetic material. Exposure to PAH's is believed to cause leukoplakia (precancerous patches on the tongue), lip and oral cavity cancers, and bladder cancer.