Benzo(a)pyrene

group inc

Revision date : 2006-06-19

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Health risk rating 1
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Environmental risk rating 1

General Information

Revision date

2006-06-19

Product name

Benzo(a)pyrene

Product Synonyms

B(A)P; BAP; BENZO(D,E,F)CHRYSENE; 3,4-BENZOPIRENE; 1,2-BENZOPYRENE; 3,4- BENZOPYRENE; 6,7-BENZOPYRENE; BENZO(A)PYRENE; 3,4-BENZPYREN; 3,4-BENZ(A)PYRENE; 3,4- BENZPYRENE; BENZ(A)PYRENE; BENZ[A]PYRENE; 3,4-BENZYLPYRENE; 3,4-BENZYPYRENE; 3,4-BP;

CAS No.

50-32-8

1.2.1 Relevant identified uses

Benzo(a)pyrene is no longer used or produced commercially in the US. In its pure form, benzo(a)pyrene may be used as a research laboratory reagent. It also occurs in combustion products of coal, oil, petroleum, wood and

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Company Information

company name

group inc

GHS Information

Signal word

Warning!

Section 2

SECTION 2: Hazards identification

Flammability Toxicity (2) Health Body Contact {Jae Reactivity ©) Chronic 1 2 3 Fire Diamond Min Low Moderate High Extreme ANSI Signal Word Warning! wowewveve Emergency Overview * % % ve Pale yellow, crystalline solid or powder. Irritating to skin, eyes, respiratory tract. Chronic Effects: carcinogen, mutagen. Handle with extreme caution!

Potential health effects

Target Organs: Respiratory system, bladder, kidneys, skin.

Principle Routes of Exposure

Inhalation, ingestion Copyright © 2006 by Genium Group, Inc. Any commercial use or reproduction without the publisher’s permission is prohibited. Judgments as to the suitability of information herein for the purchaser’ s purposes are necessarily the purchaser’s responsibility. Although reasonable care has been taken in the preparation of such information, Genium Group, Inc. extends no warranties, makes no representations, and assumes no responsibility as to the accuracy or suitability of such information for application to the purchaser’s intended purpose or for consequences of its use. Acute Effects Inhalation: Respiratory tract irritation. Pregnant women may be especially susceptible to exposure effects of benzo(a)pyrene; exposure may damage the fetus. In general, polyaromatic hydrocarbons such as benzo(a)pyrene tend to localize primarily in body fat and fatty tissues (for ex. breasts) and are excreted in breast milk. Benzo(a)pyrene may also affect the male reproductive system (testes and sperm). Eye: Irritation and/or burns on contact. Skin: Irritation with burning sensation, rash, and redness; dermatitis on prolonged exposure. Sunlight enhances effects (photosensitization). Ingestion: None reported. Carcinogenicity: NTP - Class 2B, Reasonably anticipated to be a carcinogen, sufficient evidence of carcinogenicity from studies in experimental animals; IARC - Group 2A, Probably carcinogenic to humans; OSHA - Not listed; NIOSH - Listed as carcinogen; ACGIH - Class A2, Suspected human carcinogen; EPA - Class B2, Probable human carcinogen based on animal studies; MAK - Class A2, Unmistakably carcinogenic in animal experimentation only.

Medical Conditions Generally Aggravated by Exposure

Respiratory system, bladder, kidney, and skin disorders

Potential chronic health

Inhalation Cough and bronchitis. Eye Photosensitivity and irritation. Skin Skin changes such as thickening, darkening, pimples, loss of color, reddish areas, thinning of the skin, and warts. Sunlight enhances effects (photosensitization). Other: Gastrointestinal (GI) effects include leukoplakia (a pre-cancerous condition characterized by thickened white patches of epithelium on mucous membranes, especially of the mouth). Cancer of the lung, skin, kidneys, bladder, or GI tract is also possible. Smoking in combination with exposure to benzo(a)pyrene increases the chances of developing lung cancer. Persons with a high degree of inducibility of the enzyme aryl hydrocarbon hydroxylase may be a high risk population.

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