Note: Ingredients listed on restricted chemical lists
EC/CAS
1327-53-3
Name of the chemical
Diarsenic trioxide
Concentration
N/A
EC/CAS
1310-73-2
Name of the chemical
sodium hydroxide
Concentration
N/A
EC/CAS
7732-18-5
Name of the chemical
Water, distilled, conductivity or of similar purity H2O
Concentration
N/A
General Information
Revision date
2019-05-22
Product name
Arsenic Trioxide Phebra, 1 mg/ml Concentrate For Solution For Infusion
1.2.1 Relevant identified uses
This medicine is used for the induction of remission and consolidation in patients with acute promyelocytic leukaemia (APL)
Icons in SDS
Company Information
company name
Phebra
e-mail address of the competent person responsible for the Safety Data Sheet
msds@phebra.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H302, H315, H319, H350, H412
Hazard statements
Code
Statements
H302
Harmful if swallowed
Section 2
2.1 Classification of the substance or mixture
HAZARDOUS CHEMICAL. NON-DANGEROUS GOODS. According to the WHS Regulations and the ADG Code. CHEMWATCH HAZARD RATINGS Min Max Flammability 0 Toxicity 2 0 = Minimum Body Contact 2 1 = Low 2 = Moderate Reactivity 0 3 = High Chronic 4 4 = Extreme Poisons Schedule S4 [1] Acute Toxicity (Oral) Category 4, Skin Corrosion/Irritation Category 2, Eye Irritation Category 2A, Carcinogenicity Category 1A, Chronic Aquatic Hazard Category 3 Legend: 1. Classified by Chemwatch; 2. Classification drawn from HCIS; 3. Classification drawn from Regulation (EU) No 1272/2008 - Annex VI
Signal word
DANGER
Hazard statements
H302 Harmful if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H350 May cause cancer. H412 Harmful to aquatic life with long lasting effects.
Prevention
P201 Obtain special instructions before use. P281 Use personal protective equipment as required. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection.
Response
P308+P313 IF exposed or concerned: Get medical advice/attention. P362 Take off contaminated clothing and wash before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313 If eye irritation persists: Get medical advice/attention. P301+P312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P302+P352 IF ON SKIN: Wash with plenty of soap and water. P330 Rinse mouth. P332+P313 If skin irritation occurs: Get medical advice/attention.
Storage
P405 Store locked up.
Disposal
P501 Dispose of contents/container in accordance with local regulations.
