Vfend(R)

SECTION 2: Hazards identification

Appearance: White lyophilized powder

Signal word

DANGER

Hazard statements

Harmful if swallowed. May damage the unborn child. Suspected of causing cancer. May cause damage to liver through prolonged or repeated exposure. May cause allergic skin reaction.

Additional information

Short Term: May produce slight eye irritation, Active ingredient is not a skin irritant , Accidental ingestion may cause effects similar to those seen in clinical use. Long Term: Adverse reproductive effects seen in repeat-dose animal studies are consistent with the pharmacologic action of this drug and are expected to be relevant to humans. Animal studies indicate that this material may cause adverse effects on the liver, the developing fetus. Known Clinical Effects: The most common adverse effects reported with clinical use of voriconazole include visual disturbances, elevations of liver function tests and skin rash. Voriconazole has been associated with photosensitivity skin reactions especially during long term therapy. EU Indication of danger: Toxic to Reproduction: Category 2 Carcinogenic: Category 3 Irritant EU Hazard Symbols: EU Risk Phrases: R40 - Limited evidence of a carcinogenic effect. R43 - May cause sensitization by skin contact. R61 - May cause harm to the unborn child. Note: This document has been prepared in accordance with standards for workplace safety, which require the inclusion of all known hazards of the product or its ingredients regardless of the potential risk. The precautionary statements and warnings included may not apply in all cases. Your needs may vary depending upon the potential for exposure in your workplace.