Note: Ingredients listed on restricted chemical lists
EC/CAS
232-674-9/9003-39-8
Name of the chemical
polyvinylpyrrolidone
Concentration
*
EC/CAS
209-150-3
Name of the chemical
Aluminium, zinc, magnesium and calcium stearates
Concentration
*
General Information
Revision date
2025-03-18
Product name
Tucatinib Tablets
Product name
Tucatinib Tablets
Identification on the label/Trade name
Tukysa
Product Synonyms
PF-07265792; SGD‐7715; ONT‐380; PN‐08‐0059; ARRY-432380; ARRY-380; ARRAY-380
Chemical name
Not determined
1.2.1 Relevant identified uses
Pharmaceutical product
Emergency telephone
1-800-424-9300, +1-703-527-3887
Icons in SDS
Company Information
company name
Pfizer Inc
e-mail address of the competent person responsible for the Safety Data Sheet
pfizer-MSDS@pfizer.com
GHS Information
Signal word
Warning
Hazard Codes
Hazard statements (CLP)
H361fd, H373, H411
Hazard statements
Code
Statements
H361fd
Suspected of damaging fertility; Suspected of damaging the unborn child
Section 2
SECTION 2: Hazards identification
OSHA Classification of the substance or mixture
2.3 Other hazards
Not applicable (HNOC) An Occupational Exposure Value has been established for one or more of the ingredients (see Section 8).
Signal word
Warning
Hazard statements
H373 - May cause damage to organs through prolonged or repeated exposure female reproductive system, male reproductive system H361fd - Suspected of damaging fertility. Suspected of damaging the unborn child H411 - Toxic to aquatic life with long lasting effects
Precautionary statements
P201 - Obtain special instructions before use P280 - Wear protective gloves/protective clothing/eye protection/face protection P260 - Do not breathe dust/fume/gas/mist/vapors/spray P273 - Avoid release to the environment P308 + P313 - IF exposed or concerned: Get medical advice/attention P391 - Collect spillage P405 - Store locked up P501 - Dispose of contents/container in accordance with local, regional, national, and international regulations as applicable Unknown acute toxicity 25 % of the mixture consists of ingredient(s) of unknown acute oral toxicity. 25 % of the mixture consists of ingredient(s) of unknown acute dermal toxicity. 25 % of the mixture consists of ingredient(s) of unknown acute inhalation toxicity (dust/mist).
PBT Substances
& vPvB The product does not contain any substance(s) classified as PBT or vPvB. Endocrine Disruptor Information This product does not contain any known or suspected endocrine disruptors. Note This document has been prepared in accordance with standards for workplace safety, which require the inclusion of all known hazards of the product or its ingredients regardless of the potential risk. The precautionary statements and warnings included may not apply in all cases. Your needs may vary depending upon the potential for exposure in your workplace.
2.1 Classification of the substance or mixture
GHS - Classification: Regulated according to Regulation (EC) 1272/2008 and/or other applicable regulations. Reproductive toxicity Category 2 - (H361fd) Specific target organ toxicity (repeated exposure) Category 2 - (H373) Hazardous to the aquatic environment - chronic Category 2 - (H411) OSHA Classification Hazards not otherwise classified (HNOC) Not applicable Hazards classified under paragraph (d)(1)(ii) of 1910.1200 Not applicable
