Note: Ingredients listed on restricted chemical lists
EC/CAS
215-185-5/1310-73-2
Name of the chemical
sodium hydroxide
Concentration
0.5%< >=5% <5% 0.5%<
EC/CAS
200-559-2/63-42-3
Name of the chemical
Lactose C12H22O11
Concentration
0.5%<=C<2%
EC/CAS
232-679-6/9005-25-8
Name of the chemical
Starch
Concentration
*
EC/CAS
231-791-2/7732-18-5
Name of the chemical
Water, distilled, conductivity or of similar purity H2O
Concentration
*
EC/CAS
200-413-8
Name of the chemical
Methotrexate (INN)
Concentration
2.5
EC/CAS
209-150-3
Name of the chemical
Aluminium, zinc, magnesium and calcium stearates
Concentration
*
General Information
Version
5
Revision date
2025-06-15
Product name
Methotrexate Tablets
Product name
Methotrexate Tablets
Identification on the label/Trade name
METHOBLASTIN; MAXTREX; LEDERTREXATE; NOVATREX; LANTAREL
Chemical name
Not determined
1.2.1 Relevant identified uses
Antineoplastic
Emergency telephone
1-800-424-9300, +1-703-527-3887
Icons in SDS
Company Information
company name
Pfizer Inc
e-mail address of the competent person responsible for the Safety Data Sheet
pfizer-MSDS@pfizer.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H341, H360D, H372
Hazard statements
Code
Statements
H341
Suspected of causing genetic defects
Section 2
SECTION 2: Hazards identification
OSHA Classification of the substance or mixture
2.3 Other hazards
Not applicable (HNOC) An Occupational Exposure Value has been established for one or more of the ingredients (see Section 8).
Signal word
Danger
Hazard statements
H360D - May damage the unborn child H341 - Suspected of causing genetic defects H372 - Causes damage to organs through prolonged or repeated exposure: liver, bone marrow
Precautionary statements
P201 - Obtain special instructions before use P202 - Do not handle until all safety precautions have been read and understood P260 - Do not breathe dust P264 - Wash hands thoroughly after handling P270 - Do not eat, drink or smoke when using this product P280 - Wear protective gloves and protective clothing P308 + P313 - IF exposed or concerned: Get medical advice/attention P405 - Store locked up P501 - Dispose of contents/container in accordance with local, regional, national, and international regulations as applicable
Supplemental label elements
Compound, not fully tested, additional hazards may exist.
PBT Substances
& vPvB The product does not contain any substance(s) classified as PBT or vPvB. Endocrine Disruptor Information This product does not contain any known or suspected endocrine disruptors. Note This document has been prepared in accordance with standards for workplace safety, which require the inclusion of all known hazards of the product or its ingredients regardless of the potential risk. The precautionary statements and warnings included may not apply in all cases. Your needs may vary depending upon the potential for exposure in your workplace.
2.1 Classification of the substance or mixture
GHS - Classification: Regulated according to Regulation (EC) 1272/2008 and/or other applicable regulations. Germ cell mutagenicity Category 2 - (H341) Reproductive toxicity Category 1A - (H360D) Specific target organ toxicity (repeated exposure) Category 1 - (H372) OSHA Classification Hazards not otherwise classified (HNOC) Not applicable Hazards classified under paragraph (d)(1)(ii) of 1910.1200 Not applicable
