IDAMYCIN; ZAVEDOS

SECTION 2: Hazards identification

Appearance: Red-orange lyophilised cake

Signal word

DANGER

Hazard statements

Fatal if swallowed. May damage fertility or the unborn child. Suspected of damaging fertility or the unborn child. Suspected of causing genetic defects. Suspected of causing cancer.

Additional information

Short Term: May cause skin irritation. (based on animal data) . Long Term: Repeat-dose studies in animals have shown a potential to cause adverse effects on blood and blood forming organs, gastrointestinal system, lymphatic system, male reproductive system, liver, kidneys, heart, and developing fetus. Individuals sensitive to this chemical or other materials in its chemical class may develop allergic reactions. Known Clinical Effects: Bone marrow suppression is the most serious adverse effect seen during clinical use. Adverse effects associated with the therapeutic use include effects on cardiovascular system, gastrointestinal system, liver, kidney, and skin rash. cardiac toxicity. Drugs of this class have been associated with rare, but potentially serious cardiac events. These events have not been observed from occupational exposures, however, those with preexisting cardiovascular illnesses may be at increased risk from exposure. EU Indication of danger: Very toxic Toxic to reproduction: Category 1 Carcinogenic: Category 3 Mutagenic: Category 3 EU Hazard Symbols: EU Risk Phrases: R28 - Very toxic if swallowed. R40 - Limited evidence of a carcinogenic effect R60 - May impair fertility. R61 - May cause harm to the unborn child. R68 - Possible risk of irreversible effects. Australian Hazard Classification

Hazardous Ingredients

Non-Dangerous Goods (NOHSC): Note: This document has been prepared in accordance with standards for workplace safety, which require the inclusion of all known hazards of the active substance or its intermediates regardless of the potential risk. The precautionary statements and warnings included may not apply in all cases. Your needs may vary depending upon the potential for exposure in your workplace.