Estramustine Phosphate Powder for Injection

Hazard statements (CLP)

H351, H360Df

Code

Statements

H351

Suspected of causing cancer

SECTION 2: Hazards identification

OSHA Classification of the substance or mixture

2.3 Other hazards

Not applicable (HNOC) An Occupational Exposure Value has been established for one or more of the ingredients (see Section 8). Estramustine Phosphate Pfizer OEL TWA-8 Hr: PBT & vPvB 2 µg/m3 The product does not contain any substance(s) classified as PBT or vPvB. Endocrine Disruptor Information Contains a known or suspected endocrine disruptor. Chemical name Endocrine disrupting properties in accordance with the criteria set out in Commission Delegated Regulation (EU) 2017/2100(3) or Commission Regulation (EU) 2018/605(4) Estramustine Phosphate Substance has endocrine disrupting properties Note: This document has been prepared in accordance with standards for workplace safety, which require the inclusion of all known hazards of the product or its ingredients regardless of the potential risk. The precautionary statements and warnings included may not apply in all cases. Your needs may vary depending upon the potential for exposure in your workplace.

Signal word

Danger

Hazard statements

H351 - Suspected of causing cancer H360Df - May damage the unborn child. Suspected of damaging fertility EUH380 - May cause endocrine disruption in humans EUH430 - May cause endocrine disruption in the environment

Precautionary statements

P201 - Obtain special instructions before use P202 - Do not handle until all safety precautions have been read and understood P263 - Avoid contact during pregnancy and while nursing P273 - Avoid release to the environment P280 - Wear protective gloves/protective clothing/eye protection/face protection P308 + P313 - IF exposed or concerned: Get medical advice/attention P391 - Collect spillage P405 - Store locked up P501 - Dispose of contents/container in accordance with local, regional, national, and international regulations as applicable Unknown aquatic toxicity Contains 60 % of components with unknown hazards to the aquatic environment.

2.1 Classification of the substance or mixture

GHS - Classification: Regulated according to Regulation (EC) 1272/2008 and/or other applicable regulations. Carcinogenicity Category 2 - (H351) Reproductive toxicity Category 1B - (H360Df) Endocrine disruption for human health Category 1 - (EUH380) Endocrine disruption for the environment Category 1 - (EUH430) OSHA Classification Hazards not otherwise classified (HNOC) Not applicable Hazards classified under paragraph (d)(1)(ii) of 1910.1200 Not applicable