Estradiol Vaginal Ring

Pfizer Inc

Revision date : 2025-11-01

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GHS09
Health risk rating 1
Safety risk rating 1
Environmental risk rating 5

General Information

Version

5

Revision date

2025-11-01

Product name

Estradiol Vaginal Ring

Product name

Estradiol Vaginal Ring

Identification on the label/Trade name

ESTRING; ELLESTE; OESTRING

Product Synonyms

Estradiol-17-beta

Chemical name

Steroid

1.2.1 Relevant identified uses

Pharmaceutical product used as hormone replacement therapy

Icons in SDS

GHS09 M004 M009 M010 M011 M017

Company Information

company name

Pfizer Inc

e-mail address of the competent person responsible for the Safety Data Sheet

pfizer-MSDS@pfizer.com

GHS Information

Signal word

Warning

Hazard Codes

Hazard statements (CLP)

H410

Hazard statements

Code

Statements

H410

Very toxic to aquatic life with long lasting effects

Section 2

SECTION 2: Hazards identification

OSHA Classification of the substance or mixture GHS - Classification. Hazardous to the aquatic environment - chronic Category 1 - (H410)

2.3 Other hazards

Not applicable (HNOC) An Occupational Exposure Value has been established for one or more of the ingredients (see Section 8). Estradiol Pfizer OEL TWA-8 Hr: PBT & vPvB 0.2 µg/m3, Skin The product does not contain any substance(s) classified as PBT or vPvB. Endocrine Disruptor Information See Section 11 for more information. See Section 12 for more information. Chemical name Endocrine disrupting properties in accordance with the criteria set out in Commission Delegated Regulation (EU) 2017/2100(3) or Commission Regulation (EU) 2018/605(4) Estradiol Substance has endocrine disrupting properties Note This document has been prepared in accordance with standards for workplace safety, which require the inclusion of all known hazards of the product or its ingredients regardless of the potential risk. The precautionary statements and warnings included may not apply in all cases. Your needs may vary depending upon the potential for exposure in your workplace.

Signal word

Warning

Hazard statements

H410 - Very toxic to aquatic life with long lasting effects

Precautionary statements

P273 - Avoid release to the environment P391 - Collect spillage P501 - Dispose of contents/container in accordance with local, regional, national, and international regulations as applicable

2.1 Classification of the substance or mixture

GHS - Classification. Hazardous to the aquatic environment - chronic Category 1 - (H410) OSHA Classification Hazards not otherwise classified (HNOC) Not applicable Hazards classified under paragraph (d)(1)(ii) of 1910.1200 Not applicable

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