General Information
Version
5
Revision date
2025-11-01
Product name
Estradiol Vaginal Ring
Product name
Estradiol Vaginal Ring
Identification on the label/Trade name
ESTRING; ELLESTE; OESTRING
Product Synonyms
Estradiol-17-beta
Chemical name
Steroid
1.2.1 Relevant identified uses
Pharmaceutical product used as hormone replacement therapy
Icons in SDS
Company Information
company name
Pfizer Inc
e-mail address of the competent person responsible for the Safety Data Sheet
pfizer-MSDS@pfizer.com
GHS Information
Signal word
Warning
Hazard Codes
Hazard statements (CLP)
H410
Hazard statements
Code
Statements
H410
Very toxic to aquatic life with long lasting effects
Section 2
SECTION 2: Hazards identification
OSHA Classification of the substance or mixture GHS - Classification. Hazardous to the aquatic environment - chronic Category 1 - (H410)
2.3 Other hazards
Not applicable (HNOC) An Occupational Exposure Value has been established for one or more of the ingredients (see Section 8). Estradiol Pfizer OEL TWA-8 Hr: PBT & vPvB 0.2 µg/m3, Skin The product does not contain any substance(s) classified as PBT or vPvB. Endocrine Disruptor Information See Section 11 for more information. See Section 12 for more information. Chemical name Endocrine disrupting properties in accordance with the criteria set out in Commission Delegated Regulation (EU) 2017/2100(3) or Commission Regulation (EU) 2018/605(4) Estradiol Substance has endocrine disrupting properties Note This document has been prepared in accordance with standards for workplace safety, which require the inclusion of all known hazards of the product or its ingredients regardless of the potential risk. The precautionary statements and warnings included may not apply in all cases. Your needs may vary depending upon the potential for exposure in your workplace.
Signal word
Warning
Hazard statements
H410 - Very toxic to aquatic life with long lasting effects
Precautionary statements
P273 - Avoid release to the environment P391 - Collect spillage P501 - Dispose of contents/container in accordance with local, regional, national, and international regulations as applicable
2.1 Classification of the substance or mixture
GHS - Classification. Hazardous to the aquatic environment - chronic Category 1 - (H410) OSHA Classification Hazards not otherwise classified (HNOC) Not applicable Hazards classified under paragraph (d)(1)(ii) of 1910.1200 Not applicable