Crizotinib Capsules

Hazard statements (CLP)

H317, H318, H341, H400, H410

Code

Statements

H317

May cause an allergic skin reaction

SECTION 2: Hazards identification

OSHA Classification of the substance or mixture

2.3 Other hazards

Not applicable (HNOC) An Occupational Exposure Value has been established for one or more of the ingredients (see Section 8).

Signal word

Danger

Hazard statements

H318 - Causes serious eye damage H317 - May cause an allergic skin reaction H341 - Suspected of causing genetic defects H410 - Very toxic to aquatic life with long lasting effects

Precautionary statements

P280 - Wear protective gloves/protective clothing/eye protection/face protection P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P310 - Immediately call a POISON CENTER or doctor/physician P261 - Avoid breathing dust/fume/gas/mist/vapors/spray P272 - Contaminated work clothing should not be allowed out of the workplace P333 + P313 - If skin irritation or rash occurs: Get medical advice/attention P321 - Specific treatment (see supplemental instructions on the administration of antidotes on this label) P363 - Wash contaminated clothing before reuse P202 - Do not handle until all safety precautions have been read and understood P308 + P313 - IF exposed or concerned: Get medical advice/attention P405 - Store locked up P273 - Avoid release to the environment P391 - Collect spillage P501 - Dispose of contents/container in accordance with local, regional, national, and international regulations as applicable P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

PBT Substances

& vPvB The product does not contain any substance(s) classified as PBT or vPvB. Endocrine Disruptor Information This product does not contain any known or suspected endocrine disruptors. Note This document has been prepared in accordance with standards for workplace safety, which require the inclusion of all known hazards of the product or its ingredients regardless of the potential risk. The precautionary statements and warnings included may not apply in all cases. Your needs may vary depending upon the potential for exposure in your workplace.

2.1 Classification of the substance or mixture

GHS - Classification: Regulated according to Regulation (EC) 1272/2008 and/or other applicable regulations. Serious eye damage/eye irritation Category 1 - (H318) Skin sensitization Category 1 - (H317) Germ cell mutagenicity Category 2 - (H341) Hazardous to the aquatic environment - acute Category 1 - (H400) Hazardous to the aquatic environment - chronic Category 1 - (H410) OSHA Classification Hazards not otherwise classified (HNOC) Not applicable Hazards classified under paragraph (d)(1)(ii) of 1910.1200 Not applicable