Note: Ingredients listed on restricted chemical lists
EC/CAS
202-859-9/100-51-6
Name of the chemical
Benzyl Alcohol
Concentration
0.5-1
EC/CAS
231-791-2/7732-18-5
Name of the chemical
Water, distilled, conductivity or of similar purity H2O
Concentration
limit (SCL
EC/CAS
253-149-0/36653-82-4
Name of the chemical
1-hexadecanol
Concentration
*
General Information
Version
4
Revision date
2025-07-02
Product name
Conjugated Estrogens Vaginal Cream (US)
Product name
Conjugated Estrogens Vaginal Cream (US)
Identification on the label/Trade name
PREMARIN
Product Synonyms
Estradiol-17-beta
Chemical name
Steroid
1.2.1 Relevant identified uses
Pharmaceutical product used for hormone replacement therapy
Emergency telephone
1-800-424-9300
Icons in SDS
Company Information
company name
Pfizer Inc
e-mail address of the competent person responsible for the Safety Data Sheet
pfizer-MSDS@pfizer.com
GHS Information
Signal word
Warning
Hazard Codes
Hazard statements (CLP)
H401, H410
Hazard statements
Code
Statements
H401
Toxic to aquatic life
Section 2
SECTION 2: Hazards identification
OSHA Classification of the substance or mixture
2.3 Other hazards
Not applicable (HNOC) An Occupational Exposure Value has been established for one or more of the ingredients (see Section 8).
Signal word
Warning
Hazard statements
H410 - Very toxic to aquatic life with long lasting effects
Precautionary statements
P273 - Avoid release to the environment P391 - Collect spillage
Supplemental label elements
Compound, not fully tested, additional hazards may exist. Unknown acute toxicity 0.0625 % of the mixture consists of ingredient(s) of unknown acute dermal toxicity. 0.0625 % of the mixture consists of ingredient(s) of unknown acute inhalation toxicity (dust/mist).
PBT Substances
& vPvB The product does not contain any substance(s) classified as PBT or vPvB. Endocrine Disruptor Information Contains a known or suspected endocrine disruptor. Note This document has been prepared in accordance with standards for workplace safety, which require the inclusion of all known hazards of the product or its ingredients regardless of the potential risk. The precautionary statements and warnings included may not apply in all cases. Your needs may vary depending upon the potential for exposure in your workplace.
2.1 Classification of the substance or mixture
GHS - Classification: Regulated according to Regulation (EC) 1272/2008 and/or other applicable regulations. Hazardous to the aquatic environment - acute Category 2 - (H401) Hazardous to the aquatic environment - chronic Category 1 - (H410) OSHA Classification Hazards not otherwise classified (HNOC) Not applicable Hazards classified under paragraph (d)(1)(ii) of 1910.1200 Not applicable