Conjugated Estrogens Vaginal Cream (US)

Pfizer Inc

Revision date : 2025-07-02

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GHS09
Health risk rating 1
Safety risk rating 1
Environmental risk rating 5

Note: Ingredients listed on restricted chemical lists

EC/CAS

202-859-9/100-51-6

Name of the chemical

Benzyl Alcohol

Concentration

0.5-1

EC/CAS

231-791-2/7732-18-5

Name of the chemical

Water, distilled, conductivity or of similar purity H2O

Concentration

limit (SCL

EC/CAS

200-289-5/56-81-5

Name of the chemical

glycerol

Concentration

*

EC/CAS

253-149-0/36653-82-4

Name of the chemical

1-hexadecanol

Concentration

*

General Information

Version

4

Revision date

2025-07-02

Product name

Conjugated Estrogens Vaginal Cream (US)

Product name

Conjugated Estrogens Vaginal Cream (US)

Identification on the label/Trade name

PREMARIN

Product Synonyms

Estradiol-17-beta

Chemical name

Steroid

1.2.1 Relevant identified uses

Pharmaceutical product used for hormone replacement therapy

Emergency telephone

1-800-424-9300

Icons in SDS

GHS09

Company Information

company name

Pfizer Inc

e-mail address of the competent person responsible for the Safety Data Sheet

pfizer-MSDS@pfizer.com

GHS Information

Signal word

Warning

Hazard Codes

Hazard statements (CLP)

H401, H410

Hazard statements

Code

Statements

H401

Toxic to aquatic life

Section 2

SECTION 2: Hazards identification

OSHA Classification of the substance or mixture

2.3 Other hazards

Not applicable (HNOC) An Occupational Exposure Value has been established for one or more of the ingredients (see Section 8).

Signal word

Warning

Hazard statements

H410 - Very toxic to aquatic life with long lasting effects

Precautionary statements

P273 - Avoid release to the environment P391 - Collect spillage

Supplemental label elements

Compound, not fully tested, additional hazards may exist. Unknown acute toxicity 0.0625 % of the mixture consists of ingredient(s) of unknown acute dermal toxicity. 0.0625 % of the mixture consists of ingredient(s) of unknown acute inhalation toxicity (dust/mist).

PBT Substances

& vPvB The product does not contain any substance(s) classified as PBT or vPvB. Endocrine Disruptor Information Contains a known or suspected endocrine disruptor. Note This document has been prepared in accordance with standards for workplace safety, which require the inclusion of all known hazards of the product or its ingredients regardless of the potential risk. The precautionary statements and warnings included may not apply in all cases. Your needs may vary depending upon the potential for exposure in your workplace.

2.1 Classification of the substance or mixture

GHS - Classification: Regulated according to Regulation (EC) 1272/2008 and/or other applicable regulations. Hazardous to the aquatic environment - acute Category 2 - (H401) Hazardous to the aquatic environment - chronic Category 1 - (H410) OSHA Classification Hazards not otherwise classified (HNOC) Not applicable Hazards classified under paragraph (d)(1)(ii) of 1910.1200 Not applicable

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