Axitinib Film Coated Tablets

Hazard statements (CLP)

H341, H361fd, H373, H410

Code

Statements

H341

Suspected of causing genetic defects

SECTION 2: Hazards identification

OSHA Classification of the substance or mixture

2.3 Other hazards

Not applicable (HNOC) An Occupational Exposure Value has been established for one or more of the ingredients (see Section 8). Axitinib Pfizer OEL TWA-8 Hr: PBT & vPvB 10 µg/m3 The product does not contain any substance(s) classified as PBT or vPvB. Endocrine Disruptor Information This product does not contain any known or suspected endocrine disruptors. Note This document has been prepared in accordance with standards for workplace safety, which require the inclusion of all known hazards of the product or its ingredients regardless of the potential risk. The precautionary statements and warnings included may not apply in all cases. Your needs may vary depending upon the potential for exposure in your workplace.

Signal word

Warning

Hazard statements

H341 - Suspected of causing genetic defects H361fd - Suspected of damaging fertility. Suspected of damaging the unborn child H373 - May cause damage to organs through prolonged or repeated exposure: blood and blood forming organs, bone, reproductive system, gastrointestinal system. H410 - Very toxic to aquatic life with long lasting effects EUH450 - Can cause long-lasting and diffuse contamination of water resources

Precautionary statements

P201 - Obtain special instructions before use P202 - Do not handle until all safety precautions have been read and understood P260 - Do not breathe dust P264 - Wash skin thoroughly after handling P273 - Avoid release to the environment P280 - Wear protective gloves and protective clothing P308 + P313 - IF exposed or concerned: Get medical advice/attention P391 - Collect spillage P405 - Store locked up P501 - Dispose of contents/container in accordance with local, regional, national, and international regulations as applicable 1-<5 % of the mixture consists of ingredient(s) of unknown acute dermal toxicity. 1-<5 % of the mixture consists of ingredient(s) of unknown acute inhalation toxicity (dust/mist).

2.1 Classification of the substance or mixture

GHS - Classification: Regulated according to Regulation (EC) 1272/2008 and/or other applicable regulations. Germ cell mutagenicity Category 2 - (H341) Reproductive toxicity Category 2 - (H361fd) Specific target organ toxicity (repeated exposure) Category 2 - (H373) Hazardous to the aquatic environment - acute Category 2 - (H401) Hazardous to the aquatic environment - chronic Category 1 - (H410) PMT or vPvM properties PMT - (EUH450) OSHA Classification Hazards not otherwise classified (HNOC) Not applicable Hazards classified under paragraph (d)(1)(ii) of 1910.1200 Not applicable