Bis(2-chloroethyl)ether

Health hazards

INFORMATION TOXIC FLAMMABLE Harmful to skin, eyes, and respiratory system. May be toxic if inhaled or swallowed. Avoid prolonged exposure. Do not breathe vapor. Use caution when handling. Exposure to any chemical should limited. To the best of our knowledge, the health hazards of this material have not been fully investigated. Material is for research and development purposes only EXPOSURE CONTROLS/PERSONAL PROTECTION Avoid all direct contact with product. Wear protective safety goggles. Wear chemical-resistant gloves. Wear protective clothing and boots. Ensure ventilation during use. After contact with skin, wash immediately. FIRST AID EYE CONTACT: Check for and remove any contact lenses. IMMEDIATELY flush Eyes with running water for at least 15 minutes while keeping eyes open. COLD water may be used. Seek medical attention. SKIN CONTACT: After contact with skin, wash with plenty of water. Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. COLD water may be used. Cover the irritated skin with an emollient. Seek medical attention. Wash any contaminated clothing before reusing. INHALATION: Remove victim from source of exposure to fresh air. If breathing is difficult administer oxygen. Seek medical attention. INGESTION: Do not induce vomiting. Give water to victim to drink. Seek medical attention. FIRE MEASURES Extinguishing media: carbon dioxide, dry chemical powder, alcohol or polymer foam. Special fire-fighting procedures: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Unusual fire and explosion hazards/decomposition of product: emits toxic fumes under fire conditions. HANDLING AND STORAGE INFORMATION TOXIC FLAMMABLE AVOID PROLONGED USE AVOID ALL DIRECT CONTACT WITH MATERIAL Wash thoroughly after handling. Do not breathe dust or vapor. Have safety shower and eye wash available. Do not get in eyes, on skin, on clothing. Keep container tightly closed. Store in a cool, dry, well-ventilated area. Ensure adequate ventilation during use. Use only in a chemical fume hood. Avoid sources of ignition. ACCIDENTAL RELEASE MEASURES Steps to be taken if material is released or spilled: Wear appropriate respirator, rubber boots and heavy rubber gloves. Scoop up and place in an appropriate container. Ventilate area and wash spill site after pickup is complete. Wash skin immediately with plenty of water. Absorb on sand or vermiculite and place in closed containers for disposal. DISPOSAL INFORMATION Dissolve in or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all Federal, State and local laws. PHYSICAL AND CHEMICAL PROPERTIES APPEARANCE: liquid MF: C4H8Cl2O MW: 143.01 BP: 66-67°C/15mm Hg MP: no data DEN: 1.220 Nd 20: 1.4570 FP: 55°C REACTIVITY DATA INCOMPATIBILITIES: strong oxidizing agents, strong acids and bases. HAZARDOUS DECOMPOSITION PRODUCTS: may evolve carbon monoxide, carbon dioxide, and hydrogen chloride. TOXICITY INFORMATION ACUTE EFFECTS: Toxic Irritant May be harmful by ingestion and inhalation. Material is irritating to mucous membranes and upper respiratory tract. RTECS: KN0876000 IRRITATION DATA SKN-RBT 10 MG/24H OPEN JIHTAB 30,63,1948 SKN-RBT 500 MG OPEN MLD UCDS** 12/29/1971 EYE-RBT 100 MG SEV AJOPAA 29,1363,1946 TOXICITY DATA ORL-RAT LD50: 75 MG/KG JIHTAB 30,63,1948 IHL-RAT LC50: 330 MG/M3/4H 85GMAT -,45,1982 ORL-MUS LD50: 209 MG/KG ATDAEI 1,163,1992 IHL-MUS LC50: 650 MG/M3/2H 85GMAT -,45,1982 ORL-RBT LD50: 126 MG/KG 38MKAJ 2A,2518,1981 SKN-RBT LD50: 90 MG/KG 38MKAJ 2A,2518,1981 IHL-GPG LC50: 500 PPM/1H 85JCAE -,541,1986 SKN-GPG LD50: 300 MG/KG JIHTAB 30,63,1948 ORL-MAM LD50: 112 MG/KG GISAAA 39(4),86,1974 TARGET ORGAN DATA SENSE ORGANS AND SPECIAL SENSES (PTOSIS) GASTROINTESTINAL (CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS) GASTROINTESTINAL (HYPERMOTILITY, DIARRHEA) ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR COMPLETE INFORMATION. REVIEWS, STANDARDS, AND REGULATIONS OEL=MAK ACGIH TLV-NOT CLASSIFIABLE AS A HUMAN CARCINOGEN DTLVS* TLV/BEI,1997 ACGIH TLV-STEL 58 MG/M3 (10 PPM) (SKIN) DTLVS* TLV/BEI,1997 ACGIH TLV-TWA 29 MG/M3 (5 PPM) DTLVS* TLV/BEI,1997 IARC CANCER REVIEW:ANIMAL LIMITED EVIDENCE IMEMDT 9,117,1975 IARC CANCER REVIEW:ANIMAL LIMITED EVIDENCE IMEMDT 71,1265,1999 IARC CANCER REVIEW:HUMAN NO ADEQUATE DATA IMEMDT 9,117,1975 IARC CANCER REVIEW:HUMAN INADEQUATE EVIDENCE IMEMDT 71,1265,1999 IARC CANCER REVIEW:GROUP 3 IMEMDT 71,1265,1999 MSHA STANDARD-AIR:TWA 5 PPM (30 MG/M3) (SKIN) DTLWS* 3,16,1973 OSHA PEL (GEN INDU):CL 15 PPM (90 MG/M3) (SKIN) CFRGBR 29,1910.1000,1994 OSHA PEL (CONSTRUC):CL 15 PPM (90 MG/M3) (SKIN) CFRGBR 29,1926.55,1994 OSHA PEL (SHIPYARD):CL 15 PPM (90 MG/M3) (SKIN) CFRGBR 29,1915.1000,1993 OSHA PEL (FED CONT):CL 15 PPM (90 MG/M3) (SKIN) CFRGBR 41,50-204.50,1994 OEL-AUSTRALIA:TWA 5 PPM (30 MG/M3);STEL 10 PPM (60 MG/M3);SKIN JAN 1993 OEL-AUSTRIA: MAK 5 PPM (30 MG/M3), SKIN, JAN1999 OEL-AUSTRIA:TWA 10 PPM (60 MG/M3);SKIN JAN 1993 OEL-BELGIUM:TWA 5 PPM (29 MG/M3);STEL 10 PPM (58 MG/M3);SKIN JAN 1993 OEL-FINLAND:TWA 5 PPM (30 MG/M3);STEL 10 PPM (60 MG/M3);SKIN JAN 1993 OEL-JAPAN: OEL 15 PPM (88 MG/M3), SKIN, JAN1999 OEL-GERMANY:TWA 10 PPM (60 MG/M3);SKIN JAN 1993 OEL-JAPAN:TWA 15 PPM (88 MG/M3);SKIN JAN 1993 OEL-THE NETHERLANDS:TWA 5 PPM (30 MG/M3);SKIN JAN 1993 OEL-POLAND: MAC(TWA) 10 MG/M3, MAC(STEL) 60 MG/M3, JAN1999 OEL-THE PHILIPPINES:TWA 15 PPM (90 MG/M3);SKIN JAN 1993 OEL-RUSSIA:STEL 0.6 MG/M3;SKIN JAN 1993 OEL-RUSSIA:TWA 15 PPM;STEL 2 MG/M3;SKIN JAN 1993 OEL-SWEDEN;CARCINOGEN JAN 1993 OEL-SWITZERLAND:TWA 5 PPM (30 MG/M3);STEL 25 PPM (50 MG/M3);SKIN JAN 1993 OEL-THAILAND:TWA 15 PPM (90 MG/M3) JAN 1993 OEL-TURKEY:TWA 15 PPM (90 MG/M3);SKIN JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA CHECK ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM CHECK ACGIH TLV NIOSH REL TO DICHLOROETHYLETHER-AIR:CA TWA 5 PPM (SK);STEL 10 PPM NIOSH* DHHS #92-100,1992 NOHS 1974: HZD 84164; NIS 1; TNF 21; NOS 2; TNE 41 ATSDR TOXICOLOGY PROFILE (NTIS** PB/90/168683/AS) EPA TSCA SECTION 8(B) CHEMICAL INVENTORY EPA TSCA SECTION 8(D) UNPUBLISHED HEALTH/SAFETY STUDIES ON EPA IRIS DATABASE EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, SEPTEMBER 1999 NIOSH ANALYTICAL METHOD, 1994: DICHLOROETHYL ETHER, 1004 U.S. INFORMATION THIS PRODUCT IS SUBJECT TO SARA SECTION 313 REPORTING REQUIREMENTS. THIS PRODUCT IS OR CONTAINS CHEMICAL(S) KNOWN TO THE STATE OF CALIFORNIA TO CAUSE CANCER. To the best of our knowledge, the toxicological properties of this product have not been fully determined. TRANSPORT INFORMATION Toxic liquids, flammable, organic, n.o.s. 6.1, 3 UN2929 II