MED-6385 PART A

SECTION 2: Hazards identification

EFFECTS OF SINGLE OVEREXPOSURE: SWALLOWING: Small amounts transferred to the mouth by fingers during use, etc., should not injure. Swallowing large amounts may cause digestive discomfort. SKIN ABSORPTION: No evidence of adverse effects from available information. INHALATION: Short-term harmful health effects are not expected from vapor generated at ambient temperature. SKIN CONTACT: May cause slight irritation and reddening. EYE CONTACT: May cause eye irritation, seen as excess reddening and swelling. EFFECTS OF REPEATED OVEREXPOSURE: No injury from silica or other dust should occur during reasonable use. If use creates respirable particles, then some respiratory system injury may occur. However, since the silica in this product is compounded into the polymer matrix, it is not expected to present the same health hazards as neat silica.

Medical Conditions Generally Aggravated by Exposure

OVEREXPOSURE A knowledge of the available toxicology information and of the physical and chemical properties of the material suggests that overexposure is unlikely to aggravate existing medical conditions. SIGNIFICANT LABORATORY DATA WITH POSSIBLE RELEVANCE TO HUMAN HEALTH HAZARD EVALUATION: Diatomaceous earth may contain up to 75 % crystalline silica, which is classified by the International Agency for Research on Cancer (IARC) as a class 2A carcinogen (probably carcinogenic to humans: limited human evidence, sufficient evidence in experimental animals); and by the National Toxicology Program (NTP) as a class 2 carcinogen (reasonably anticipated to be a carcinogen: limited evidence from studies in humans or sufficient evidence from studies in experimental animals). The EPA has expressed concern regarding the possible adverse health effects resulting from the inhalation of alkoxylsilanes and has recommended that administrative and mechanical means be used to minimize exposures. OTHER EFFECTS OF OVEREXPOSURE: None currently known.