PROPYLENE GLYCOL USP

SECTION 2: Hazards identification

OSHA Emergency Overview Appearance: liquid, colourless MAY AFFECT THE CENTRAL NERVOUS SYSTEM CAUSING DIZZINESS, HEADACHE OR NAUSEA.

Principle Routes of Exposure

Inhalation, Skin absorption, Skin contact, Eye Contact, Ingestion Kye contact May cause mild eye irritation. Symptoms include stinging, tearing, and redness. Skin contact Unlikely to cause skin irritation or injury. Ingestion Swallowing small amounts of this material during normal handling is not likely to cause harmful effects. Swallowing large amounts may be harmful. Inhalation 1.4 87556 It is possible to breathe this material under certain conditions of handling and use (for example, during heating, spraying, or stirring). Breathing small amounts of this material during normal handling is not likely to cause harmful effects. Breathing large amounts may be harmful. Symptoms are not expected at air concentrations below the recommended exposure limits, if applicable (see Section 8.).

Medical Conditions Generally Aggravated by Exposure

Preexisting disorders of the following organs (or organ systems) may be aggravated by exposure to this material:, lung (for example, asthma-like conditions), Kidney Symptoms Signs and symptoms of exposure to this material through breathing, swallowing, and/or passage of the material through the skin may include:, irritation (nose, throat, airways), central nervous system depression (dizziness, drowsiness, weakness, fatigue, nausea, headache, unconsciousness) Target Organs Overexposure to this material (or its components) has been suggested as a cause of the following effects in laboratory animals:, kidney damage Carcinogenicity This material is not listed as a carcinogen by the International Agency for Research on Cancer (IARC), the National Toxicology Program (NTP), or the Occupational Safety and Health Administration

Further information

Propylene glycol may be absorbed in potentially harmful amounts when applied in large quantities to severe burns (second or third degree) over large areas of the body as part of a cream or other topical application. Absorption under such circumstances can elevate serum osmolality and may result in osmotic shock.