Reveal 2.0 for DSP

Hazard statements (CLP)

H314, H335

Code

Statements

H314

Causes severe skin burns and eye damage

SECTION 2: Hazards identification

Signal word

Danger

Hazard statements

H314: Causes severe skin burns and eye damage H335: May cause respiratory irritation

Precautionary statements

P280: Wear protective gloves/protective clothing/eye protection/face protection. P305/351/338 IF IN EYES Rinse cautiously with water for several minutes Remove contact lenses, if present and easy to do. Continue rinsing. P310: Immediately call a POISON CENTER or doctor/physician.

2.3 Other hazards

None known Page 1 of 6 Rev. 0, February 2013

2.1 Classification of the substance or mixture

EU Directives 67/548/EEC or 1999/45/EC Sodium Hydroxide Solution -Skin corrosion (Category 1A) R35: Causes severe burns -Skin corrosion/Irritation (Category 2) R36/37/38: Irritating to the eyes, -Serious eye damage/Eye irritation respiratory system and skin. Hydrochloric Acid Solution (Category 2) -Specific target organ systemic toxicity (single exposure) (Category 3) 2.2 Label Elements Labelling according to Regulation (EC) No 1272/2008 [CLP] Pictogram Signal Word Danger Hazard Statements H314: Causes severe skin burns and eye damage H335: May cause respiratory irritation Precautionary Statements P280: Wear protective gloves/protective clothing/eye protection/face protection. P305/351/338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310: Immediately call a POISON CENTER or doctor/physician. Other Hazards None known Page 1 of 6 Rev 0, February 2013 Section 3. Composition/Information on Ingredients 3.2 Mixtures: (For the full text of the H-Statements and R-phrases mentioned in this Section, see Section 16.) Components Classification Sodium hydroxide solution CAS No. 1310-73-2 Skin Corr. 1A; H314 Concentration: 62% EC No. 215-185-5 C; R35 Index No. 011-002-00-6 Hydrochloric acid solution CAS No. 7647-01-0 Skin Corr. 1B; H314; STOT SE 3; H335 Concentration: 50% EC No. 231-595-7 C; R34; X1; R37 Index No. 017-002-01-X Section 4. First Aid Measures 4.1 Description of First Ingestion: DO NOT INDUCE VOMITING. If swallowed, seek medical attention immediately. Aid: Wash out mouth with water, provided person is conscious. Show physician product label. Inhalation: If inhaled, supply fresh air or oxygen. Seek medical attention if breathing is laboured or becomes difficult. If not breathing, apply artificial respiration. Eye Contact: Rinse opened eye for at least 15 minutes under running water, lifting lower and upper eyelids occasionally. Immediate medical attention is required. Skin Contact: Remove contaminated clothing. Immediately wash with plenty of soap and water for at least 15 minutes. Seek medical attention immediately. Wash clothing before reuse. 4.2 Most Important Burning sensation, cough, wheezing, laryngitis, shortness of breath, spasm, inflammation and Symptoms and Effects, oedema of the larynx, spasm, inflammation and oedema of the bronchi, pneumonitis, pulmonary Both Acute and oedema. Material is extremely destructive to tissue of the mucous membranes and upper Delayed respiratory tract, eyes and skin. 4.3 Indication of Any No data available Immediate Medical Attention and Special Treatment Needed Section 5. Firefighting Measures 5.1 Extinguishing Media Suitable extinguishing media: Use alcohol-resistant foam, dry chemical, or carbon dioxide. Unsuitable extinguishing media: None known 5.2 Special Hazards Arising from the Substance or Mixture: Contact with metals may evolve flammable hydrogen gas. Thermal decomposition can lead to release of irritating gases and vapours. 5.3 Advice for Firefighters: Firefighters should wear protective equipment and self-contained breathing apparatus. Section 6. Accidental Release Measures 6.1 Personal Precautions, Protective Equipment and Emergency Procedures: Use personal protective equipment. Place contaminated material in a chemical waste container. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. 6.2 Environmental Precautions: Prevent dispersion of material. Do not let produce enter drains. 6.3 Methods and Materials for Containment and Cleaning Up: Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. If questions arise contact safety officer. 6.4 Reference to Other Sections: For disposal see section 13. Page 2 of 6 Rev 0, February 2013 Section 7. Handling and Storage 7.1 Precautions for Safe Handling: Wear appropriate personal protective equipment. Ensure good ventilation / exhaustion and do not breathe vapour or mist. Avoid contact with eyes, skin, and clothing. 7.2 Conditions for Safe Storage, Including Any Incompatibilities: Keep container tightly closed in a cool, well-ventilated area. Do not store in metal containers. 7.3 Specific End Uses: No data available Section 8. Exposure Controls / Personal Protection Components with limit values that require monitoring: Not Applicable 8.1 Control Parameters (Exposure Limits) Sodium hydroxide solution: STEL: 2 mg/m3 (UK EH40 WEL – Workplace Exposure Limits) Hydrochloric acid solution: STEL: 8 mg/m3 (UK EH40 WEL – Workplace Exposure Limits) 8.2 Exposure Controls Appropriate Engineering Controls: Personal Protection listed below are general requirements for laboratory personnel. Follow the usual precautionary measures for handling chemicals / liquid. Avoid contact with eyes, skin, and clothing. Wash hands before breaks and at the end of the workday. Ensure eyewash stations and safety showers are close to the workstation location. Personal Protective Equipment: Eye/Face Protection: Tightly fitting safety goggles or face shield. Use equipment for eye protection tested and approved under appropriate government standards such as EN 166. Skin and Body Protection: Protective gloves that satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Use proper glove removal techniques to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Wear long-sleeved clothing. Wash contaminated clothing before reuse. Respiratory Protection: When workers are facing concentration above the exposure limit, they must use appropriate certified respirators. Section 9. Physical and Chemical Properties 9.1 Information on Basic Physical and Chemical Properties a) Appearance Colourless liquid b) Odour Hydrochloric Acid: Sharp, disagreeable odour c) Odour threshold Sodium hydroxide solution Hydrochloric acid solution d) pH: 14.0 0.1 e) Freezing point: -12 - 10°C -17°C f) Boiling point: 105 - 140°C 81. - 110°C g) Flash point: Not applicable, not flammable h) Evaporation rate No information available i) Flammability (solid, gas) Not applicable, liquid j) LEL/UEL Not flammable k) Vapour pressure < 24 hPa at 20°C 160 mm Hg at 20°C l) Vapour density 1.38 (Air = 1.0) 1.26 (Air = 1.0) m) Relative density 1.327 1.05-1.12 n) Water solubility Completely miscible, soluble Soluble Page 3 of 6 Rev 0, February 2013 Section 9. Physical and Chemical Properties (cont’d) 9.1 Information on Basic Physical and Chemical Properties (cont’d) Sodium hydroxide solution (cont’d) Hydrochloric acid solution (cont’d) o) Partition coefficient No information available p) Autoignition temperature No information available q) Decomposition temperature No information available r) Viscosity No information available s) Explosive properties No information available t) Oxidizing properties No information available 9.2 Other information: No information available Section 10. Stability and Reactivity 10.1 Reactivity: No data available 10.2 Chemical Stability: Stable under normal conditions 10.3 Possibility of Hazardous Reactions: May react with metals and lead to form flammable hydrogen gas 10.4 Conditions to Avoid: Excess heat; incompatible substances 10.5 Incompatible Materials: Acids, aldehydes, aluminium, bases, chlorinated solvents, metals, organic materials, oxidizing agents, phosphorus, reducing agents, tin/tin oxide, zinc Hazardous Decomposition Products: Hydrogen chloride gas Section 11. Toxicological Information 11.1 Information on Toxicological Effects Sodium hydroxide solution Hydrochloric acid solution a) Acute toxicity Oral, rat LD50: >90 mL/kg Oral, rat LD50: 700 mg/kg b) Skin corrosion/irritation Skin, rabbit: 500 mg/24hr severe No data available c) Serious eye damage/irritation Eye, rabbit: 1 mg/24hr severe No data available d) Respiratory or skin sensitisation No data available e) Germ cell mutagenicity No data available Mutagenic effects have occurred in experimental animals f) Carcinogenicity Not listed (IARC, ACGIH, NTP) IARC Group 3 g) Reproductive toxicity No data available Experiments have shown reproductive toxicity effects on laboratory animals h) STOT-single exposure No data available Skin, eyes Respiratory system, skin, eyes, i) STOT-repeated exposure No data available gastrointestinal tract (GI), liver, kidney, blood, teeth j) Aspiration hazard No data available No data available Potential health effects Inhalation: May be harmful if inhaled. Material is extremely destructive to the tissue of the mucous membranes and upper respiratory tract. Ingestion: May be harmful if swallowed. Causes burns. Skin: May be harmful if absorbed through the skin. Causes skin burns. Eyes: Causes eye burns. Page 4 of 6 Rev 0, February 2013 Section 11. Toxicological Information (cont’d) 11.1 Information on Toxicological Effects (cont’d) Signs and symptoms of exposure Burning sensation, cough, wheezing, laryngitis, shortness of breath, spasm, inflammation and oedema of the larynx, spasm, inflammation and oedema of the bronchi, pneumonitis, pulmonary oedema. Material is extremely destructive to the tissue of the mucous membranes and upper respiratory tract. Section 12. Ecological Information 12.1 Toxicity: Hydrochloric Acid: Fresh water fish 282 mg/L LC50 96h Sodium Hydroxide: No data available 12.2 Persistence and Degradability: No data available 12.3 Bioaccumulative Potential: No data available 12.4 Mobility in Soil: No data available 12.5 Results of PBT and vPvB Assessment: No data available 12.6 Other Adverse Effects: None known Section 13. Disposal Considerations 13.1 Waste Treatment Methods: Product should be disposed of with a licensed waste disposal company, while following all regional, local and national regulations. Section 14. Transport Information ADR/RID IMDG IATA 14.1 UN Number 1760 14.2 UN Proper Shipping Name Corrosive, liquid, n.o.s. 14.3 Transport Hazard Class 8 14.4 Packing Group II 14.5 Environmental Hazards No Marine pollutant: No No 14.6 Special Precautions for User No information available Page 5 of 6 Rev 0, February 2013 Section 15. Regulatory Information 15.1 Safety, Health and Environmental Regulations/Legislation Specific for the Substance or Mixture International Inventories: Hydrochloric Acid: EINECS ELINCS TSCA DSL NDSL PICCS ENCS CHINA AICS KECL 231-595-7 - T X - X KE-20189 Legend: EINECS/ELINCS – European Inventory Lists TSCA – United States Toxic Substances Control Act Inventory, Section 8(b) DSL/NDSL – Canadian Domestic Substances List/Non-Domestic Substances List PICCS – Philippines Inventory of Chemicals and Chemical Substances ENCS – Japan Existing and New Chemical Substances CHINA – China Inventory of Existing Chemical Substances AICS – Inventory of Chemical Substances KECL – Existing and Evaluated Chemical Substances 15.2 Chemical Safety Assessment No data available Section 16. Other Information H314: Causes severe skin burns and eye damage H335: May cause respiratory irritation R35: Causes severe burns R37: Irritating to respiratory system R36/37/38: Irritating to eyes, respiratory system and skin. This safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006. This document is believed to be correct, but does not purport to be all inclusive and shall be used only as a guide. Neogen Corporation shall not be held liable for any damage resulting from handling or from contact with the above product. These suggestions should not be confused with state, municipal or insurance requirements, and constitute NO WARRANTY. Page 6 of 6 Rev 0, February 2013