R-123

Hazard statements (CLP)

H336

Code

Statements

H336

May cause drowsiness or dizziness

SECTION 2: Hazards identification

OSHA CLASSIFICATION Specific Target Organ Toxicity (Central Nervous System) – Single Exposure Category 3

Signal word

WARNING HAZARD STATEMENT May cause drowsiness or dizziness SYMBOL Exclamation Mark

Prevention

Avoid breathing vapors

Response

If inhaled move victim to fresh air and keep at rest in a position comfortable for breathing

Storage

Store in a well-ventilated place. Keep container tightly closed. Store locked up

Disposal

Dispose of contents/container at an approved disposal facility EMERGENCY OVERVIEW: Colorless, volatile liquid with ethereal and faint sweetish odor. Non-flammable material. Overexposure may cause dizziness and loss of concentration. At higher levels, CNS depression and cardiac arrhythmia may result from exposure. Vapors displace air and can cause asphyxiation in confined spaces. At higher temperatures, (>250C), decomposition products may include Hydrochloric Acid (HCI), Hydrofluoric Acid (HF) and carbonyl halides.

Health hazards

SKIN: Prolonged and/or repeated contact with this solvent can cause irritation of the skin (defatting of skin). EYES: Irritant. Liquid contact will irritate and may cause conjunctivitis. INHALATION: When oxygen levels in air are reduced to 12-14% by displacement, symptoms of asphyxiation, loss of coordination, increased pulse rate and deeper respiration will occur. Overexposure to vapors may cause temporary anesthetic effects such as dizziness, headache and confusion. At higher levels, cardiac arrhythmia may occur. In repeated exposure tests with animals, changes were noted in liver functions and lipid production at levels above 100 ppm. In isolated incidents with workers, overexposure to solvent vapors resulted in elevated liver enzyme levels. Liver enzyme levels returned to normal after overexposure ceased. R-123 INGESTION: Discomfort due to volatility would be expected. Some of the inhalation effects could be expected. DELAYED EFFECTS: No delayed effects of a single exposure have been identified. Delayed effects of multiple exposure are seen in animal studies by the formation late developing benign tumors. Repeated overexposure to vapor may result in elevated liver enzyme levels.

2.1 Classification of the substance or mixture

Specific Target Organ Toxicity (Central Nervous System) – Single Exposure Category 3 SIGNAL WORD: WARNING HAZARD STATEMENT: May cause drowsiness or dizziness SYMBOL