This Standard Reference Material (SRM) is a gravimetrically prepared single-compound solution

NFPA Ratings

Scale 0–4) Health = 2 Fire = 3 Reactivity = 0 NOTE: This 1,1,1-trichloroethane in methanol solution has not been tested as a whole. The health and physical hazard information are for 1,1,1-trichloroethane and methanol. The actual effects of the solution may differ from the individual components.

Health hazards

Skin, eye, and/or respiratory tract irritation, central nervous system depression, nerve damage, aspiration hazard.

Physical hazards

Flammable liquid and vapor. Vapor may cause flash fire. Electrostatic charges may be generated by flow or agitation.

Potential health effects

Acute and Chronic) Inhalation: Methanol may cause irritation, cough, ringing in the ears, constipation, headache, drowsiness, dizziness, tingling sensation, pain in extremities, tremors, loss of coordination, blood disorders, and nerve damage. Exposure to 900-1000 ppm of 1,1,1-trichloroethane for twenty minutes may cause mild respiratory tract irritation. Skin Contact: Methanol can cause irritation, absorption may occur, headache, drowsiness, dizziness, loss of coordination, and blood disorders. 1,1,1-trichloroethane may cause irritation and redness. Eye Contact: Methanol vapors may cause irritation and eye damage. Repeated or prolonged contact may cause conjunctivitis. 1,1,1-Trichloroethane may cause the same effects as methanol. Ingestion: Ingestion of methanol may result in mild and transient inebriation, and subsequent drowsiness. Liver, kidney, heart, stomach, intestine and pancreatic damage may also occur. Death may occur due to respiratory failure. As little as 15 mL has caused blindness; the usual fatal dose is 60–240 mL. Ingestion of 1,1,1-trichloroethane may cause nausea, vomiting, gastrointestinal disturbances, central nervous system depression, headache, dizziness. Listed as a Carcinogen/Potential Carcinogen Yes No In the National Toxicology Program (NTP) Report on Carcinogens X In the International Agency for Research on Cancer (IARC) Monographs X(a) By the Occupational Safety and Health Administration (OSHA) X (a)IARC lists 1,1,1-trichloroethane as Group 3 (not classifiable). 3. COMPOSITION AND INFORMATION ON HAZARDOUS INGREDIENTS Component CAS Number EC Number Nominal Mass Concentration(a) (EINECS) (%) Methanol 67-56-1 200-659-6 99 1,1,1-Trichloroethane 71-55-6 200-756-3 1