SequaGel XR

Appearance/Odor

Clear, colorless solution. EMERGENCY OVERVIEW - IMMEDIATE HAZARD WARNING! HARMFUL IF SWALLOWED. MAY CAUSE ALLERGIC SKIN REACTION. MAY CAUSE EYE IRRITATION. POLYMERIZATION MAY OCCUR FROM EXCESSIVE HEAT OR CONTAMINATION. EMERGENCY OVERVIEW - CHRONIC HAZARD WARNING CHRONIC TOXICITY HAZARD. ACRYLAMIDE MAY CAUSE NERVOUS SYSTEM DAMAGE. ACRYLAMIDE CAUSED CANCER AND MALE REPRODUCTIVE DISORDERS IN LABORATORY ANIMAL TESTS. RISK DEPENDS ON DURATION AND LEVEL OF EXPOSURE.

Potential health effects

Inhalation Inhalation of mist causes irritation to the respiratory tract. Symptoms may parallel ingestion. Ingestion Toxic! May cause systemic poisoning. May cause drowsiness, tingling sensations, fatigue, weakness, stumbling, slurred speech, and shaking. May cause central and peripheral nervous system damage. Severe intoxication may cause permanent nerve damage. May affect reproductive system and act as a teratogen. Skin May cause irritation and redness. Can be absorbed through the skin causing systemic poisoning; symptoms may parallel ingestion. Eyes Acrylamide solutions may cause eye irritation. Signs and Symptoms of Overexposure Inhalation Contact with this material by inhalation of mist may cause nervous system effects. See ingestion effects for more details. Ingestion Contact with this material by any route (eyes/skin, inhalation or ingestion) may cause nervous system effects (neurotoxicity). These effects can result from a single overexposure but are more likely to occur after repeated exposures to small amounts over a period of several days or weeks. Signs and symptoms of toxic effects include increased sweating of the hands and feet, numbness, tingling and weakness in the extremeties, unsteady gait and decreased reflexes Skin Acrylamide is readily absorbed through unbroken skin. If the exposure route is dermal, the signs and symptoms described above under 'Signs and Symptoms of Overexposure - Ingestion' may be preceded by peeling and redness of skin at the areas of exposure, normally the hands and feet. Eyes Contact with this material by eyes may cause nervous system effects. See 'Signs and Symptoms of Overexposure - Ingestion' above for more details. Carcinogenicity Acrylamide is suspected as a cancer hazard. May cause cancer. Listed by NTP as a suspected carcinogen. Acrylamide is known to the State of California to cause cancer. Mutagenicity Acrylamide was negative in the Ames assay both with and without metabolic activation. Reproductive Toxicitiy Acrylamide induced male reproductive toxicity has been demonstrated in Long-Evans rats where given greater than or equal to 15 mg/kg/day acrylamide orally by gavage for five consecutive days. In this study, males receiving greater than or equal to 15 mg/kg/day acrylamide had a reduced fertility index.

Teratogenic Effects

Not Available.

Principle Routes of Exposure

Contact with this material by any route of exposure (eye/skin, inhalation or ingestion) may cause serious adverse health consequences. Target Organ Statement Not Available.