Note: Ingredients listed on restricted chemical lists
General Information
Version
5.2
Revision date
2025-04-14
Product name
Vorinostat Formulation
1.2.1 Relevant identified uses
Pharmaceutical
Emergency telephone
1-908-423-6000
Icons in SDS
Company Information
company name
MSD
e-mail address of the competent person responsible for the Safety Data Sheet
EHSDATASTEWARD@msd.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H303, H341, H360FD, H372, H410
Hazard statements
Code
Statements
H303
May be harmful if swallowed
Section 2
SECTION 2: Hazards identification
GHS Classification GHS Classification Acute toxicity (Oral) Category 5 Germ cell mutagenicity Category 2 Reproductive toxicity Category 1B Specific target organ toxicity - repeated exposure (Oral) Category 1 (Blood, thymus gland, Bone marrow, spleen, Gas- trointestinal tract) Short-term (acute) aquatic Category 1 hazard Long-term (chronic) aquatic Category 1 hazard
Signal word
Danger
Hazard statements
H303 May be harmful if swallowed. H341 Suspected of causing genetic defects. H360FD May damage fertility. May damage the unborn child. H372 Causes damage to organs (Blood, thymus gland, Bone marrow, spleen, Gastrointestinal tract) through prolonged or repeated exposure if swallowed. H410 Very toxic to aquatic life with long lasting effects.
Prevention
P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protec- tion/ face protection.
Response
P312 Call a POISON CENTER/ doctor if you feel unwell. P391 Collect spillage.
Storage
P405 Store locked up.
Disposal
P501 Dispose of contents/ container to an approved waste disposal plant.
Other hazards which do not result in classification
Dust contact with the eyes can lead to mechanical irritation. Contact with dust can cause mechanical irritation or drying of the skin. May form explosive dust-air mixture during processing, handling or other means.
2.1 Classification of the substance or mixture
Acute toxicity (Oral) : Category 5 Germ cell mutagenicity : Category 2 Reproductive toxicity : Category 1B Specific target organ toxicity - : Category 1 (Blood, thymus gland, Bone marrow, spleen, Gas- repeated exposure (Oral) trointestinal tract) Short-term (acute) aquatic : Category 1 hazard Long-term (chronic) aquatic : Category 1 hazard
