Temozolomide Injection Formulation

Hazard statements (CLP)

H303, H319, H341, H351, H360FD, H373

Code

Statements

H303

May be harmful if swallowed

SECTION 2: Hazards identification

Manufacture, Storage and Import of Hazardous Chemicals Rules 1989 Classification Not classified as hazardous according to criteria laid down in Part I of Schedule-1 GHS Classification Acute toxicity (Oral) Category 5 Serious eye damage/eye irri- tation Category 2A Germ cell mutagenicity Category 2 Carcinogenicity Category 2 Reproductive toxicity Category 1B Specific target organ toxicity - repeated exposure (Oral) Category 2 (Bone marrow, thymus gland, Lymph nodes, spleen)

Signal word

Danger

Hazard statements

H303 May be harmful if swallowed. H319 Causes serious eye irritation. H341 Suspected of causing genetic defects. H351 Suspected of causing cancer. H360FD May damage fertility. May damage the unborn child. H373 May cause damage to organs (Bone marrow, thymus gland, Lymph nodes, spleen) through prolonged or repeated exposure if swallowed.

Prevention

P203 Obtain, read and follow all safety instructions before use. P260 Do not breathe dust. P264 + P265 Wash hands thoroughly after handling. Do not touch eyes. P280 Wear protective gloves/ protective clothing/ eye protec- tion/ face protection.

Response

P301 + P337 + P317 IF SWALLOWED or if eye irritation per- sists: Get medical help. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P318 IF exposed or concerned, get medical advice.

Storage

P405 Store locked up.

Disposal

P501 Dispose of contents/ container to an approved waste disposal plant.

Other hazards which do not result in classification

Contact with dust can cause mechanical irritation or drying of the skin. May form explosive dust-air mixture during processing, handling or other means.

2.1 Classification of the substance or mixture

Not classified as hazardous according to criteria laid down in Part I of Schedule-1. GHS Classification Acute toxicity (Oral) : Category 5 Serious eye damage/eye irri- : Category 2A tation Germ cell mutagenicity : Category 2 Carcinogenicity : Category 2 Reproductive toxicity : Category 1B Specific target organ toxicity - : Category 2 (Bone marrow, thymus gland, Lymph nodes, repeated exposure (Oral) spleen)