Note: Ingredients listed on restricted chemical lists
EC/CAS
77-92-9
Name of the chemical
Citric acid
Concentration
>=10-<20
General Information
Version
12.1
Revision date
2025-12-06
Product name
Temozolomide Injection Formulation
1.2.1 Relevant identified uses
Pharmaceutical
Icons in SDS
Company Information
company name
MSD
e-mail address of the competent person responsible for the Safety Data Sheet
EHSDATASTEWARD@msd.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H319, H341, H351, H360FD, H373
Hazard statements
Code
Statements
H319
Causes serious eye irritation
Section 2
SECTION 2: Hazards identification
GHS Classification Serious eye damage/eye irri- tation Category 2A Germ cell mutagenicity Category 2 Carcinogenicity Category 2 Reproductive toxicity Category 1B Specific target organ toxicity - repeated exposure (Oral) Category 2 (Bone marrow, thymus gland, Lymph nodes, spleen)
Signal word
Danger
Hazard statements
H319 Causes serious eye irritation. H341 Suspected of causing genetic defects. H351 Suspected of causing cancer. H360FD May damage fertility. May damage the unborn child. H373 May cause damage to organs (Bone marrow, thymus gland, Lymph nodes, spleen) through prolonged or repeated exposure if swallowed.
Prevention
P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust. P264 Wash skin thoroughly after handling. P280 Wear protective gloves/ protective clothing/ eye protec- tion/ face protection.
Response
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ at- tention.
Storage
P405 Store locked up.
Disposal
P501 Dispose of contents/ container to an approved waste disposal plant.
Other hazards which do not result in classification
Contact with dust can cause mechanical irritation or drying of the skin. May form explosive dust-air mixture during processing, handling or other means.
2.1 Classification of the substance or mixture
Serious eye damage/eye irri- : Category 2A tation Germ cell mutagenicity : Category 2 Carcinogenicity : Category 2 Reproductive toxicity : Category 1B Specific target organ toxicity - : Category 2 (Bone marrow, thymus gland, Lymph nodes, repeated exposure (Oral) spleen)
