Note: Ingredients listed on restricted chemical lists
EC/CAS
201-069-1/77-92-9
Name of the chemical
Citric acid
Concentration
>=10-<20
General Information
Version
12.2
Revision date
2025-01-23
Product name
Temozolomide Injection Formulation
1.2.1 Relevant identified uses
Pharmaceutical
Emergency telephone
353-51-601000, +1-908-423-6000
Icons in SDS
Company Information
company name
MSD
e-mail address of the competent person responsible for the Safety Data Sheet
EHSDATASTEWARD@msd.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H319, H341, H351, H360FD, H373
Hazard statements
Code
Statements
H319
Causes serious eye irritation
Section 2
SECTION 2: Hazards identification
Regulation (EC) No. 1272/2008 Classification of the substance or mixture
Signal word
Danger
Hazard statements
H319 Causes serious eye irritation. H341 Suspected of causing genetic defects. H351 Suspected of causing cancer. H360FD May damage fertility. May damage the unborn child. H373 May cause damage to organs through prolonged or repeated exposure.
Prevention
P201 Obtain special instructions before use. P260 Do not breathe dust. P264 Wash skin thoroughly after handling. P280 Wear protective gloves/ protective clothing/ eye protec- tion/ face protection.
Response
P308 + P313 IF exposed or concerned: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention.
Hazardous Ingredients
Temozolomide
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumula- tive and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
ECOLOGICAL INFORMATION
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regu- lation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
TOXICOLOGICAL INFORMATION
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. Contact with dust can cause mechanical irritation or drying of the skin. May form explosive dust-air mixture during processing, handling or other means.
2.1 Classification of the substance or mixture
Classification (REGULATION (EC) No 1272/2008) Eye irritation, Category 2 H319: Causes serious eye irritation. Germ cell mutagenicity, Category 2 H341: Suspected of causing genetic defects. Carcinogenicity, Category 2 H351: Suspected of causing cancer. Reproductive toxicity, Category 1B H360FD: May damage fertility. May damage the unborn child. Specific target organ toxicity - repeated H373: May cause damage to organs through pro- exposure, Category 2 longed or repeated exposure.
