Temozolomide Formulation

MSD

Revision date : 2025-01-23

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GHS08 GHS07
Health risk rating 5
Safety risk rating 1
Environmental risk rating 1

Note: Ingredients listed on restricted chemical lists

EC/CAS

201-766-0/87-69-4

Name of the chemical

L-(+)-tartaric acid

Concentration

>=1-<3

General Information

Version

8.2

Revision date

2025-01-23

Product name

Temozolomide Formulation

1.2.1 Relevant identified uses

Pharmaceutical

Emergency telephone

+27 11 655 3000, +1-908-423-6000

Icons in SDS

GHS07 GHS08

Company Information

company name

MSD

e-mail address of the competent person responsible for the Safety Data Sheet

EHSDATASTEWARD@msd.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H302, H319, H341, H351, H360FD, H372

Hazard statements

Code

Statements

H302

Harmful if swallowed

Section 2

SECTION 2: Hazards identification

Regulation (EC) No. 1272/2008 Classification of the substance or mixture

Signal word

Danger

Hazard statements

H302 Harmful if swallowed. H319 Causes serious eye irritation. H341 Suspected of causing genetic defects. H351 Suspected of causing cancer. H360FD May damage fertility. May damage the unborn child. H372 Causes damage to organs through prolonged or re- peated exposure.

Prevention

P201 Obtain special instructions before use. P260 Do not breathe dust. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/ protective clothing/ eye protec- tion/ face protection.

Response

P308 + P313 IF exposed or concerned: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/

Hazardous Ingredients

Temozolomide

Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumula- tive and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. Contact with dust can cause mechanical irritation or drying of the skin. May form explosive dust-air mixture during processing, handling or other means

2.1 Classification of the substance or mixture

Classification (REGULATION (EC) No 1272/2008) Acute toxicity, Category 4 H302: Harmful if swallowed. Eye irritation, Category 2 H319: Causes serious eye irritation. Germ cell mutagenicity, Category 2 H341: Suspected of causing genetic defects. Carcinogenicity, Category 2 H351: Suspected of causing cancer. Reproductive toxicity, Category 1B H360FD: May damage fertility. May damage the unborn child. Specific target organ toxicity - repeated H372: Causes damage to organs through pro- exposure, Category 1 longed or repeated exposure.

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