Temozolomide Formulation

MSD

Revision date : 2024-12-19

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GHS08 GHS07
Health risk rating 5
Safety risk rating 1
Environmental risk rating 1

Note: Ingredients listed on restricted chemical lists

EC/CAS

57-11-4

Name of the chemical

stearic acid

Concentration

>=1-<5

EC/CAS

87-69-4

Name of the chemical

L-(+)-tartaric acid

Concentration

>=1-<3

General Information

Version

10.0

Revision date

2024-12-19

Product name

Temozolomide Formulation

1.2.1 Relevant identified uses

Pharmaceutical

supplier name

MSD

Emergency telephone

1-908-423-6000

Icons in SDS

GHS07 GHS08

Company Information

company name

MSD

e-mail address of the competent person responsible for the Safety Data Sheet

EHSDATASTEWARD@msd.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H302, H319, H341, H351, H360FD, H372

Hazard statements

Code

Statements

H302

Harmful if swallowed

Section 2

SECTION 2: Hazards identification

GHS Classification GHS Classification Acute toxicity (Oral) Category 4 Serious eye damage/eye irritation Category 2A Germ cell mutagenicity Category 2 Carcinogenicity Category 2 Reproductive toxicity Category 1B Specific target organ toxicity - repeated exposure (Oral) Category 1 (Bone marrow, thymus gland, Lymph nodes, spleen)

Signal word

Danger

Hazard statements

H302 Harmful if swallowed. H319 Causes serious eye irritation. H341 Suspected of causing genetic defects. H351 Suspected of causing cancer. H360FD May damage fertility. May damage the unborn child. H372 Causes damage to organs (Bone marrow, thymus gland, Lymph nodes, spleen) through prolonged or repeated exposure if swallowed.

Prevention

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.

Response

P301 + P312 + P330 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell. Rinse mouth. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ atten- tion.

Storage

P405 Store locked up.

Disposal

P501 Dispose of contents/ container to an approved waste dis- posal plant.

Other hazards

Contact with dust can cause mechanical irritation or drying of the skin. May form explosive dust-air mixture during processing, handling or other means

2.1 Classification of the substance or mixture

Acute toxicity (Oral) : Category 4 Serious eye damage/eye : Category 2A irritation Germ cell mutagenicity : Category 2 Carcinogenicity : Category 2 Reproductive toxicity : Category 1B Specific target organ toxicity : Category 1 (Bone marrow, thymus gland, Lymph nodes, spleen) - repeated exposure (Oral)

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