Imipenem / Cilastatin / Relebactam Formulation

Hazard statements (CLP)

H319, H334, H361d, H373, H410

Code

Statements

H319

Causes serious eye irritation

SECTION 2: Hazards identification

GHS Classification GHS Classification Serious eye damage/eye irri- tation Category 2 Respiratory sensitisation Category 1 Reproductive toxicity Category 2 Specific target organ toxicity - Category 2 (Kidney) repeated exposure Hazardous to the aquatic Category 1 environment - acute hazard Hazardous to the aquatic Category 1 environment - chronic hazard

Signal word

Danger

Hazard statements

H319 Causes serious eye irritation. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H361d Suspected of damaging the unborn child. H373 May cause damage to organs (Kidney) through pro- longed or repeated exposure. H410 Very toxic to aquatic life with long lasting effects.

Prevention

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P261 Avoid breathing dust. P264 Wash skin thoroughly after handling. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protec- tion/ face protection. P284 Wear respiratory protection.

Response

P304 + P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ at- tention. P342 + P311 If experiencing respiratory symptoms: Call a POISON CENTER/ doctor. P391 Collect spillage.

Storage

P405 Store locked up.

Disposal

P501 Dispose of contents/ container to an approved waste disposal plant.

Other hazards which do not result in classification

Contact with dust can cause mechanical irritation or drying of the skin. May form explosive dust-air mixture during processing, handling or other means.

2.1 Classification of the substance or mixture

Serious eye damage/eye irri- : Category 2 tation Respiratory sensitisation : Category 1 Reproductive toxicity : Category 2 Specific target organ toxicity - : Category 2 (Kidney) repeated exposure Hazardous to the aquatic : Category 1 environment - acute hazard Hazardous to the aquatic : Category 1 environment - chronic hazard