Methotrexate

Merck Sdn. Bhd

Revision date : 2024-04-02

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GHS08 GHS06
Health risk rating 5
Safety risk rating 1
Environmental risk rating 1

Note: Ingredients listed on restricted chemical lists

EC/CAS

200-413-8

Name of the chemical

Methotrexate (INN)

Concentration

100%

General Information

Version

8.7

Revision date

2024-04-02

Product name

Methotrexate

CAS No.

59-05-2

1.2.1 Relevant identified uses

Reagent for development and research

Emergency telephone

+60 (0)3-74943688, +60 (0)3-74910850, +60 3- 9212 5794

Icons in SDS

GHS06 GHS08

Company Information

company name

Merck Sdn. Bhd

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H301, H341, H360D, H372

Hazard statements

Code

Statements

H301

Toxic if swallowed

Section 2

SECTION 2: Hazards identification

EU Classification

CLASS regulations 2013 Acute toxicity, Oral (Category 3), H301 Germ cell mutagenicity (Category 2), H341 Reproductive toxicity (Category 1B), H360D Specific target organ toxicity - repeated exposure (Category 1), Liver, Bone marrow, H372 For the full text of the H-Statements mentioned in this Section, see Section 16.

2.2 Label elements

Labelling according to CLASS regulations 2013

Signal word

Danger

Hazard statements

H301 Toxic if swallowed. H341 Suspected of causing genetic defects. H360D May damage the unborn child. H372 Causes damage to organs (Liver, Bone marrow) through prolonged or repeated exposure.

Prevention

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P281 Use personal protective equipment as required.

Response

P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician. Rinse mouth. P308 + P313 IF exposed or concerned: Get medical advice/ attention.

Storage

P405 Store locked up.

Disposal

P501 Dispose of contents/ container to an approved waste disposal plant.

Other hazards

- none SECTION 3: Composition and information of the ingredients of the hazardous chemical

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