(-)-Nicotine Msynth plus

Merck Life Science (Pty) Ltd

Revision date : 2024-03-21

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GHS09 GHS06
Health risk rating 5
Safety risk rating 1
Environmental risk rating 4

Note: Ingredients listed on restricted chemical lists

EC/CAS

200-193-3/54-11-5

Name of the chemical

Nicotine and its salts

Concentration

<= 100 %

General Information

Version

9.4

Revision date

2024-03-21

Product name

(-)-Nicotine Msynth plus

CAS No.

54-11-5

REACH No

A

1.2.1 Relevant identified uses

Pharmaceutical production

Icons in SDS

GHS06 GHS09

Company Information

company name

Merck Life Science (Pty) Ltd

e-mail address of the competent person responsible for the Safety Data Sheet

Melissa.byrne@merckgroup.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H300, H300+H310+H330, H310, H315, H318, H330, H411

Hazard statements

Code

Statements

H300

Fatal if swallowed

Section 2

SECTION 2: Hazards identification

Regulation (EC) No. 1272/2008 Classification of the substance or mixture Acute toxicity, (Category 1) H300: Fatal if swallowed Acute toxicity, (Category 2) H330: Fatal if inhaled Acute toxicity, (Category 2) H310: Fatal in contact with skin. Skin irritation, (Category 2) H315: Causes skin irritation. Serious eye damage, (Category H318: Causes serious eye damage. 1) Long-term (chronic) aquatic H411: Toxic to aquatic life with long lasting hazard, (Category 2) effects.

Signal word

Danger Danger

Hazard statements

H300 + H310 + H330 Fatal if swallowed, in contact with skin or if inhaled. H315 Causes skin irritation. H318 Causes serious eye damage. H411 Toxic to aquatic life with long lasting effects. H318 Causes serious eye damage. H300 + H310 + H330 Fatal if swallowed, in contact with skin or if inhaled.

Precautionary statements

P262 Do not get in eyes, on skin, or on clothing. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P302 + P352 + P310 IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/ doctor. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P262 Do not get in eyes, on skin, or on clothing. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P302 + P352 + P310 IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/ doctor. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Supplemental label elements

none Reduced Labeling (<= 125 ml) none

Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

2.1 Classification of the substance or mixture

Acute toxicity, (Category 1) H300: Fatal if swallowed. Acute toxicity, (Category 2) H330: Fatal if inhaled. Acute toxicity, (Category 2) H310: Fatal in contact with skin. Skin irritation, (Category 2) H315: Causes skin irritation. Serious eye damage, (Category H318: Causes serious eye damage. 1) Long-term (chronic) aquatic H411: Toxic to aquatic life with long lasting hazard, (Category 2) effects.

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