4,4′-Methylenebis(phenyl isocyanate)

Hazard statements (CLP)

H315, H317, H319, H332, H334, H335, H351, H373

Code

Statements

H315

Causes skin irritation

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

Acute toxicity, (Category 4) H332: Harmful if inhaled. Skin irritation, (Category 2) H315: Causes skin irritation. Eye irritation, (Category 2) H319: Causes serious eye irritation. Respiratory sensitization, H334: May cause allergy or asthma (Category 1) symptoms or breathing difficulties if inhaled. Skin sensitization, (Category 1) H317: May cause an allergic skin reaction. Carcinogenicity, (Category 2) H351: Suspected of causing cancer. Specific target organ toxicity - H335: May cause respiratory irritation. single exposure, (Category 3), Respiratory system Specific target organ toxicity - H373: May cause damage to organs repeated exposure, (Category 2), through prolonged or repeated exposure if Respiratory system inhaled.

2.2 Label elements

Labelling

Signal word

Danger Danger

Hazard statements

H315 Causes skin irritation. H317 May cause an allergic skin reaction. H319 Causes serious eye irritation. H332 Harmful if inhaled. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H335 May cause respiratory irritation. H351 Suspected of causing cancer. H373 May cause damage to organs (Respiratory system) through prolonged or repeated exposure if inhaled. "As from 24 August 2023 adequate training is required before industrial or professional use." Reduced Labeling (<= 125 ml) H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H317 May cause an allergic skin reaction. H351 Suspected of causing cancer.

Precautionary statements

P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P302 + P352 IF ON SKIN: Wash with plenty of water. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P202 Do not handle until all safety precautions have been read and understood. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P302 + P352 IF ON SKIN: Wash with plenty of water. P308 + P313 IF exposed or concerned: Get medical advice/ attention.

Supplemental label elements

none none

2.3 Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. Lachrymator.