General Information
Version
8.3
Revision date
2025-03-25
Product name
Human CRISPR Activation Calabrese Library
Emergency telephone
+(45)-6991 8573, +(45)-8212 1212
Icons in SDS
Company Information
company name
Merck Life Science ApS
e-mail address of the competent person responsible for the Safety Data Sheet
TechnicalService@merckgroup.com
Section 2
SECTION 2: Hazards identification
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008. Classification of the substance or mixture
2.3 Other hazards
Biohazard, Biosafety Level 2, Lentiviruses are a subset of retroviruses, with the ability to integrate into host chromosomes, and to infect non-dividing cells. These viruses can cause severe immunologic and neurologic disease in their natural hosts. Lentivirus vector systems can include viruses of non-human/non-primate origin . The more recent generation vectors have been designed to significantly diminish the possibility for recombination to occur resulting in a wild type- potentially infectious virus. Typical lentivirus vectors are packaged using pseudotyped enveloped proteins. It is usually recommended that work with nonhuman lentiviruses that are incapable of establishing productive infections in humans be conducted at BSL-2. Work with simian or human lentiviruses is typically conducted at a higher containment level. genetically modified organism
2.1 Classification of the substance or mixture
Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008.