Note: Ingredients listed on restricted chemical lists
EC/CAS
407-25-0
Name of the chemical
Trifluoroacetic anhydride
Concentration
>= 60 - <= 100
General Information
Version
9.1
Revision date
2026-08-11
Product name
Trifluoroacetic anhydride
CAS No.
407-25-0
1.2.1 Relevant identified uses
For R&D use only. Not for pharmaceutical, household or other uses
Emergency telephone
+61 2 9037 2994
Icons in SDS
Company Information
company name
Merck Life Science Pty Ltd
e-mail address of the competent person responsible for the Safety Data Sheet
customersupport.anz@merckgroup.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H314, H332, H361, H412
Hazard statements
Code
Statements
H314
Causes severe skin burns and eye damage
Section 2
SECTION 2: Hazards identification
GHS Classification Acute toxicity (Inhalation) Category 4 Skin corrosion/irritation Sub-category 1A Serious eye damage/eye irritation Category 1 Reproductive toxicity Category 2 Long-term (chronic) Category 3 aquatic hazard
Signal word
Danger
Hazard statements
H314 Causes severe skin burns and eye damage. H332 Harmful if inhaled. H361 Suspected of damaging fertility or the unborn child. H412 Harmful to aquatic life with long lasting effects.
Supplemental label elements
AUH014 Reacts violently with water.
Prevention
P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P261 Avoid breathing mist or vapours. P264 Wash skin thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
Response
P301 + P330 + P331 + P310 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER/ doctor. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immedi- ately call a POISON CENTER/ doctor. P305 + P351 + P338 + P310 IF IN EYES: Rinse cau- tiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P363 Wash contaminated clothing before reuse.
Storage
P405 Store locked up.
Disposal
P501 Dispose of contents/ container to an approved waste disposal plant.
Other hazards which do not result in classification
None known.
2.1 Classification of the substance or mixture
Acute toxicity (Inhalation) : Category 4 Skin corrosion/irritation : Sub-category 1A Serious eye damage/eye : Category 1 irritation Reproductive toxicity : Category 2 Long-term (chronic) : Category 3 aquatic hazard
