General Information
Version
6.7
Revision date
2025-12-26
Product name
Protease from Bacillus licheniformis
Emergency telephone
+33 (0)9 75 18 14 07, +33 (0)1 45 42 59 59
Icons in SDS
Company Information
company name
Merck Life Science S.A.S
e-mail address of the competent person responsible for the Safety Data Sheet
servicetechnique@merckgroup.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H315, H318, H334, H335, H400, H410, H411
Hazard statements
Code
Statements
H315
Causes skin irritation
Section 2
SECTION 2: Hazards identification
Regulation (EC) No. 1272/2008 Classification of the substance or mixture
Signal word
Danger Danger
Hazard statements
H315 Causes skin irritation. H318 Causes serious eye damage. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H335 May cause respiratory irritation. H410 Very toxic to aquatic life with long lasting effects. H318 Causes serious eye damage. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary statements
P273 Avoid release to the environment. P280 Wear eye protection/ face protection. P280 Wear eye protection/ face protection. P305 + P351 + P338 + IF IN EYES: Rinse cautiously with water for several minutes. P310 Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor.
Response
P302 + P352 IF ON SKIN: Wash with plenty of water. P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor.
Hazardous Ingredients
subtilisin Reduced Labelling (<= 125 ml)
Supplemental label elements
none
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
ECOLOGICAL INFORMATION
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
TOXICOLOGICAL INFORMATION
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
2.1 Classification of the substance or mixture
Classification (REGULATION (EC) No 1272/2008) Skin irritation, Category 2 H315: Causes skin irritation. Serious eye damage, Category 1 H318: Causes serious eye damage. Respiratory sensitisation, Category H334: May cause allergy or asthma 1 symptoms or breathing difficulties if inhaled. Specific target organ toxicity - H335: May cause respiratory irritation. single exposure, Category 3, Respiratory system Short-term (acute) aquatic hazard, H400: Very toxic to aquatic life. Category 1 Long-term (chronic) aquatic hazard, H411: Toxic to aquatic life with long lasting Category 2 effects.