Protease from Bacillus licheniformis

Merck Life Science S.A.S

Revision date : 2025-12-26

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GHS08 GHS05 GHS07 GHS09
Health risk rating 5
Safety risk rating 1
Environmental risk rating 5

General Information

Version

6.7

Revision date

2025-12-26

Product name

Protease from Bacillus licheniformis

Emergency telephone

+33 (0)9 75 18 14 07, +33 (0)1 45 42 59 59

Icons in SDS

GHS05 GHS07 GHS08 GHS09 M004 M009 M011

Company Information

company name

Merck Life Science S.A.S

e-mail address of the competent person responsible for the Safety Data Sheet

servicetechnique@merckgroup.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H315, H318, H334, H335, H400, H410, H411

Hazard statements

Code

Statements

H315

Causes skin irritation

Section 2

SECTION 2: Hazards identification

Regulation (EC) No. 1272/2008 Classification of the substance or mixture

Signal word

Danger Danger

Hazard statements

H315 Causes skin irritation. H318 Causes serious eye damage. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H335 May cause respiratory irritation. H410 Very toxic to aquatic life with long lasting effects. H318 Causes serious eye damage. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Precautionary statements

P273 Avoid release to the environment. P280 Wear eye protection/ face protection. P280 Wear eye protection/ face protection. P305 + P351 + P338 + IF IN EYES: Rinse cautiously with water for several minutes. P310 Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor.

Response

P302 + P352 IF ON SKIN: Wash with plenty of water. P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor.

Hazardous Ingredients

subtilisin Reduced Labelling (<= 125 ml)

Supplemental label elements

none

2.3 Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

2.1 Classification of the substance or mixture

Classification (REGULATION (EC) No 1272/2008) Skin irritation, Category 2 H315: Causes skin irritation. Serious eye damage, Category 1 H318: Causes serious eye damage. Respiratory sensitisation, Category H334: May cause allergy or asthma 1 symptoms or breathing difficulties if inhaled. Specific target organ toxicity - H335: May cause respiratory irritation. single exposure, Category 3, Respiratory system Short-term (acute) aquatic hazard, H400: Very toxic to aquatic life. Category 1 Long-term (chronic) aquatic hazard, H411: Toxic to aquatic life with long lasting Category 2 effects.

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